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蔓越莓提取物漱口水与含氟漱口水对6至12岁儿童常规龋齿管理辅助作用的疗效比较评估:一项随机对照试验。

Comparative Assessment of Efficacy of Cranberry Extract Mouthwash and Fluoride Mouthwash on Count as an Adjunct to Conventional Caries Management among 6-12-year-old Children: A Randomized Controlled Trial.

作者信息

Agrawal Arushi, Padawe Dimple, Takate Vilas, Kharat Sanath, Sachdev Sanpreet S

机构信息

Department of Pediatric and Preventive Dentistry, Government Dental College and Hospital, Mumbai, Maharashtra, India.

Department of Oral Pathology and Microbiology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Mumbai, Maharashtra, India.

出版信息

Int J Clin Pediatr Dent. 2025 Feb;18(2):198-202. doi: 10.5005/jp-journals-10005-3053. Epub 2025 Mar 20.

Abstract

BACKGROUND

Dental caries remains a prevalent oral health concern among children worldwide, necessitating effective preventive measures. This study evaluates the efficacy of cranberry extract mouthwash and fluoride mouthwashes in reducing counts among children aged 6-12 years with moderate to severe dental caries.

MATERIALS AND METHODS

A randomized controlled trial was conducted involving children with three or more carious lesions [Caries Assessment Spectrum and Treatment (CAST) types 3-9]. Participants were assigned to receive either cranberry extract mouthwash or fluoride mouthwash, administered weekly for 6 months. colony-forming units (CFUs) were assessed at baseline, 3 months, and 6 months to measure bacterial load reduction.

RESULTS

Both cranberry extract mouthwash and fluoride mouthwashes demonstrated statistically significant reductions in CFUs at 3 months ( < 0.01) and 6 months ( < 0.01) compared to baseline. No significant difference was observed between the two mouthwashes, suggesting comparable efficacy in bacterial count reduction.

CONCLUSION

This study supports the use of cranberry extract mouthwash as a natural alternative to fluoride mouthwash in managing dental caries among children. Both interventions effectively reduced counts, highlighting their potential as adjuncts to conventional caries management strategies.

HOW TO CITE THIS ARTICLE

Agrawal A, Padawe D, Takate V, Comparative Assessment of Efficacy of Cranberry Extract Mouthwash and Fluoride Mouthwash on Count as an Adjunct to Conventional Caries Management among 6-12-year-old Children: A Randomized Controlled Trial. Int J Clin Pediatr Dent 2025;18(2):198-202.

摘要

背景

龋齿仍是全球儿童普遍关注的口腔健康问题,因此需要有效的预防措施。本研究评估了蔓越莓提取物漱口水和含氟漱口水在减少6至12岁中度至重度龋齿儿童口腔细菌数量方面的功效。

材料与方法

进行了一项随机对照试验,纳入有三个或更多龋损病变(龋病评估光谱和治疗[CAST]类型3 - 9)的儿童。参与者被分配接受蔓越莓提取物漱口水或含氟漱口水,每周使用一次,共6个月。在基线、3个月和6个月时评估菌落形成单位(CFU),以测量细菌载量的减少。

结果

与基线相比,蔓越莓提取物漱口水和含氟漱口水在3个月(P < 0.01)和6个月(P < 0.01)时均显示出CFU的统计学显著降低。两种漱口水之间未观察到显著差异,表明在减少细菌数量方面具有相当的功效。

结论

本研究支持将蔓越莓提取物漱口水作为含氟漱口水的天然替代品用于儿童龋齿管理。两种干预措施均有效减少了细菌数量,突出了它们作为传统龋齿管理策略辅助手段的潜力。

如何引用本文

阿格拉瓦尔A、帕达韦D、塔卡特V,蔓越莓提取物漱口水和含氟漱口水作为6 - 12岁儿童传统龋齿管理辅助手段对口腔细菌数量影响的疗效比较评估:一项随机对照试验。《国际临床儿科牙科学杂志》2025年;18(2):198 - 202。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/315e/12099230/a9a926b86a26/ijcpd-18-2-198-g001.jpg

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