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一名有频繁使用抗生素史的26岁女性因[具体病因未给出]导致的需氧菌性阴道炎

Aerobic Vaginitis Caused By and in a 26-Year-Old Woman with a History of Frequent Antibiotics Administration.

作者信息

Achdiat Pati Aji, Saraswati Amalia Laksmi, Handayani Yulisa, Rowawi Rasmia, Maharani Retno Hesty

机构信息

Department of Dermatology and Venereology, Faculty of Medicine Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, West Java, Indonesia.

出版信息

Int J Womens Health. 2025 May 19;17:1437-1444. doi: 10.2147/IJWH.S516616. eCollection 2025.

DOI:10.2147/IJWH.S516616
PMID:40417640
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12101460/
Abstract

Aerobic vaginitis (AV) is a form of vaginitis caused by the presence of aerobic bacteria, primarily , and . This condition is characterized by clinical signs of acute inflammation, including vaginal redness, burning, increased vaginal secretions with a pH of 5, sticky vaginal discharge, leukocyte infiltration, and vulvar pruritus, which is defined as itching and irritation, and commonly occurs in individuals between the age of 15-30 years and 31-45 years. The report presents a case of AV caused by and in a 26-year-old female patient at Hasan Sadikin Hospital, Bandung. The treatment process includes the administration of amoxicillin 500 mg three times daily for 14 days. The patient was unmarried, routinely performed vaginal douching with betel soap, and frequently used a panty liner. Subsequently, a history of frequent antibiotic use was reported, however, the specific names of previously administered antibiotics remain unknown, except for clindamycin, which is the only agent specifically recalled. The patient also had a history of high exposure to stressors and underwent a bacterial culture examination taken from the vaginal introitus, which showed the presence of and . This case highlights the significance of AV in the differential diagnosis of vaginal infections, especially in atypical patient populations, and emphasizes the need for appropriate diagnostic measures such as bacterial culture to guide effective treatment strategies.

摘要

需氧菌性阴道炎(AV)是一种由需氧菌引起的阴道炎,主要是[具体细菌1]和[具体细菌2]。这种情况的特征是急性炎症的临床症状,包括阴道发红、灼痛、阴道分泌物增多(pH值为5)、阴道分泌物粘稠、白细胞浸润以及外阴瘙痒(定义为瘙痒和刺激),常见于15至30岁以及31至45岁的人群。该报告介绍了万隆哈桑·萨迪金医院一名26岁女性患者由[具体细菌1]和[具体细菌2]引起的需氧菌性阴道炎病例。治疗过程包括每日三次服用500毫克阿莫西林,持续14天。该患者未婚,常规使用槟榔皂进行阴道灌洗,且经常使用护垫。随后,报告了频繁使用抗生素的病史,然而,除了唯一明确提及的克林霉素外,之前使用的抗生素具体名称不详。该患者还曾有高压力暴露史,并接受了阴道前庭的细菌培养检查,结果显示存在[具体细菌1]和[具体细菌2]。该病例突出了需氧菌性阴道炎在阴道感染鉴别诊断中的重要性,尤其是在非典型患者群体中,并强调了采取适当诊断措施(如细菌培养)以指导有效治疗策略的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4316/12101460/221312d03e40/IJWH-17-1437-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4316/12101460/eadd270c993b/IJWH-17-1437-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4316/12101460/59457ba5aebb/IJWH-17-1437-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4316/12101460/5f2c9e887dec/IJWH-17-1437-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4316/12101460/221312d03e40/IJWH-17-1437-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4316/12101460/eadd270c993b/IJWH-17-1437-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4316/12101460/59457ba5aebb/IJWH-17-1437-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4316/12101460/5f2c9e887dec/IJWH-17-1437-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4316/12101460/221312d03e40/IJWH-17-1437-g0004.jpg

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本文引用的文献

1
Aerobic Vaginitis Caused by Enterococcus Faecalis - Clinical Features and Treatment.粪肠球菌引起的需氧菌性阴道炎——临床特征与治疗
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2
Bacterial Vaginosis: What Do We Currently Know?细菌性阴道病:我们目前了解多少?
Front Cell Infect Microbiol. 2022 Jan 18;11:672429. doi: 10.3389/fcimb.2021.672429. eCollection 2021.
3
Pathogen profile and risk factors of aerobic vaginitis in pregnant women: a retrospective cohort study.孕妇需氧性阴道炎的病原体特征及危险因素:一项回顾性队列研究。
Ann Palliat Med. 2021 Aug;10(8):8881-8888. doi: 10.21037/apm-21-1710.
4
Psychosocial Stress, Cortisol Levels, and Maintenance of Vaginal Health.心理社会压力、皮质醇水平与阴道健康的维持
Front Endocrinol (Lausanne). 2018 Sep 24;9:568. doi: 10.3389/fendo.2018.00568. eCollection 2018.
5
Aerobic vaginitis: no longer a stranger.需氧菌性阴道炎:不再陌生。
Res Microbiol. 2017 Nov-Dec;168(9-10):845-858. doi: 10.1016/j.resmic.2017.04.004. Epub 2017 May 11.
6
Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa.菌群失调诱导的白细胞介素-33导致生殖黏膜抗病毒免疫受损。
Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):E762-71. doi: 10.1073/pnas.1518589113. Epub 2016 Jan 25.
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Curr Infect Dis Rep. 2015 May;17(5):477. doi: 10.1007/s11908-015-0477-6.
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Diagnostic and therapeutic advancements for aerobic vaginitis.需氧菌性阴道炎的诊断与治疗进展
Arch Gynecol Obstet. 2015 Feb;291(2):251-7. doi: 10.1007/s00404-014-3525-9. Epub 2014 Nov 4.
9
Aerobic vaginitis and mixed infections: comparison of clinical and laboratory findings.需氧性阴道炎与混合感染:临床与实验室检查结果的比较。
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Gynecol Obstet Invest. 2010;70(4):244-9. doi: 10.1159/000314013. Epub 2010 Oct 16.