Aliberti Angelo, Gasparro Roberta, Triassi Maria, Piscopo Mirko, Ausiello Pietro, Tribst João Paulo Mendes
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via Sergio Pansini 5, 80131 Naples, Italy.
Interdepartmental Research Centre in Health Management and Innovation in Healthcare (CIRMIS), Via Sergio Pansini 5, 80131 Naples, Italy.
Dent J (Basel). 2025 May 21;13(5):224. doi: 10.3390/dj13050224.
Dental caries remains a prevalent issue in pediatric dentistry, necessitating restorative materials that not only repair decay but also provide protective benefits. Fluoride-releasing restorative materials have a key function in preventing recurrent caries by inhibiting bacterial activity and promoting remineralization. The objective of this study was to examine fluoride release from three pediatric dental restorative materials-, , and the -under different pH and temperature conditions. : Specimens (10 mm diameter and 2 mm thickness; n = 3 for each material) were prepared according to the manufacturers' instructions; immersed in buffer solutions at pH 4.8, 6.8, and 8.8; and stored at 37 °C and 44 °C. Fluoride release was quantified using ion chromatography at three time points (1 day, 7 days, and 28 days). : The data revealed that fluoride release was significantly influenced by pH, temperature, and time ( < 0.05). exhibited the highest release, particularly in acidic conditions (pH 4.8), reaching 40.14 mg/L at 44 °C after 28 days. The and also showed increased release over time, but with lower cumulative concentrations. Higher temperatures generally enhanced fluoride diffusion across all materials. : These findings emphasize the pivotal impact of environmental factors in fluoride release dynamics. demonstrated superior fluoride release, particularly in acidic environments, suggesting its potential for high-caries-risk pediatric patients. These insights can inform the selection of restorative materials in pediatric dentistry, optimizing caries prevention strategies.
龋齿仍然是儿童牙科领域的一个普遍问题,因此需要不仅能修复龋坏还能提供保护作用的修复材料。含氟修复材料在抑制细菌活性和促进再矿化以预防继发龋方面具有关键作用。本研究的目的是检测三种儿童牙科修复材料——[材料名称1]、[材料名称2]和[材料名称3]——在不同pH值和温度条件下的氟释放情况。方法:按照制造商的说明制备样本(直径10毫米,厚度2毫米;每种材料n = 3);将其浸入pH值为4.8、6.8和8.8的缓冲溶液中;并在37℃和44℃下储存。在三个时间点(1天、7天和28天)使用离子色谱法定量氟释放量。结果:数据显示,氟释放受到pH值、温度和时间的显著影响(P < 0.05)。[材料名称1]释放量最高,尤其是在酸性条件下(pH 4.8),在44℃下28天后达到40.14毫克/升。[材料名称2]和[材料名称3]的释放量也随时间增加,但累积浓度较低。较高的温度通常会增强所有材料的氟扩散。结论:这些发现强调了环境因素对氟释放动态的关键影响。[材料名称1]表现出卓越的氟释放性能,尤其是在酸性环境中,表明其对高龋齿风险的儿童患者具有潜在应用价值。这些见解可为儿童牙科修复材料的选择提供参考,优化龋齿预防策略。