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The effect of nicotine on ethanol-induced gastric ulcers in rats.

作者信息

Ogle C W, Cho C H, Wong S H

出版信息

Experientia. 1985 Sep 15;41(9):1140-1. doi: 10.1007/BF01951697.

DOI:10.1007/BF01951697
PMID:4043323
Abstract

Nicotine, in concentrations of 5 and 25 micrograms/ml drinking water, given ad libitum for 10 days, dose-dependently increased lesion formation and worsened ethanol-induced ulceration in rat stomachs. Daily fluid intake and b.wt gain were not adversely affected by nicotine pretreatment.

摘要

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本文引用的文献

1
Effect of nicotine on the morphology of the rat gastric mucosa.
Gastroenterology. 1980 Jun;78(6):1488-94.
2
The effect of nicotine pretreatment on the gastric mucosal damage induced by aspirin and reserpine in rats.尼古丁预处理对阿司匹林和利血平诱导的大鼠胃黏膜损伤的影响。
Life Sci. 1984 Feb 20;34(8):751-6. doi: 10.1016/0024-3205(84)90382-5.
3
Cigarettes, alcohol, coffee and peptic ulcer.香烟、酒精、咖啡与消化性溃疡。
N Engl J Med. 1974 Feb 28;290(9):469-73. doi: 10.1056/NEJM197402282900901.
尼古丁诱导的胃损伤。硫糖铝和喂养保护作用的定量宏观和微观分析。
Gut. 1991 Apr;32(4):372-6. doi: 10.1136/gut.32.4.372.
4
The influence of chronic nicotine treatment on stress-induced gastric ulceration and emptying rate in rats.
Experientia. 1992 Apr 15;48(4):389-91. doi: 10.1007/BF01923437.