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11-酮睾酮和睾酮对褐鳟(Salmo trutta L.)皮肤结构的影响

The effects of 11-ketotestosterone and testosterone on the skin structure of brown trout, Salmo trutta L.

作者信息

Pottinger T G, Pickering A D

出版信息

Gen Comp Endocrinol. 1985 Sep;59(3):335-42. doi: 10.1016/0016-6480(85)90389-2.

DOI:10.1016/0016-6480(85)90389-2
PMID:4043719
Abstract

11-Ketotestosterone and testosterone were administered by intraperitoneal implants to immature brown trout. Physiological levels of circulating androgens were maintained over a period of 4 months and this resulted in changes in skin structure which resembled those occurring in maturing male brown trout. 11-Ketotestosterone promoted both epidermal and dermal thickening, and markedly reduced the number of superficial goblet cells, whereas testosterone stimulated only epidermal thickening. The relative roles of these two androgens in the normal maturational processes of brown trout are discussed.

摘要

通过腹腔植入法将11 - 酮睾酮和睾酮施用于未成熟的褐鳟。在4个月的时间里维持了循环雄激素的生理水平,这导致皮肤结构发生变化,类似于成熟雄性褐鳟的皮肤变化。11 - 酮睾酮促进了表皮和真皮增厚,并显著减少了表层杯状细胞的数量,而睾酮仅刺激表皮增厚。讨论了这两种雄激素在褐鳟正常成熟过程中的相对作用。

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