定制红细胞：通往血液安全的漫长道路。 - Suppr

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超能文献

Tailor-made red cells: the long road towards blood safety.

作者信息

Mijovic Aleksandar

机构信息

King's College Hospital, Denmark Hill, London SE5 9RS.

出版信息

Haematologica. 2025 Sep 1;110(9):1909-1911. doi: 10.3324/haematol.2025.287882. Epub 2025 May 29.

DOI:10.3324/haematol.2025.287882

PMID:40438987

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12399930/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3652/12399930/97ec23bfbec4/1101909.fig1.jpg

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Generation of 'designer erythroblasts' lacking one or more blood group systems from CRISPR/Cas9 gene-edited human-induced pluripotent stem cells.利用 CRISPR/Cas9 基因编辑的人类诱导多能干细胞生成缺乏一种或多种血型系统的“设计红细胞”。

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