Martindah Eny, Noor Susan Maphilindawati, Wahyuwardani Sutiastuti, Wasito Wasito, Hewajuli Dyah Ayu, Putri Riyandini, Prihandani Sri Suryatmiati, Andriani Andriani, Sumirah Sumirah, Mulyadi Andi, Azizah Naila Arsy Kun
Research Centre for Veterinary Science, The National Research and Innovation Agency, Cibinong Science Centre, Jl. Raya Jakarta-Bogor KM. 46, Bogor, 16911, Indonesia.
Department of Remote Sensing, Faculty of Geography, Universitas Gadjah Mada, Bulaksumur, Yogyakarta, 55281, Indonesia.
Vet World. 2025 Apr;18(4):888-895. doi: 10.14202/vetworld.2025.888-895. Epub 2025 Apr 19.
Brucellosis, caused by spp., is a zoonotic disease of major public health and economic significance. In Indonesia, surveillance efforts have predominantly focused on bovine brucellosis, leaving limited data on small ruminants despite their critical role as disease reservoirs. This study aims to estimate the seroprevalence of brucellosis in goats and sheep and to identify potential risk factors associated with its transmission in the Jabodetabek region, Indonesia.
A cross-sectional study was conducted from May 2023 to November 2023, involving 18 herds of goats and sheep across Jakarta, Bogor, Depok, Tangerang, and Bekasi. A total of 665 blood samples (355 from goats and 310 from sheep) and 112 milk samples were collected. The samples were analyzed using the Rose Bengal Test, complement fixation test, and enzyme-linked immunosorbent assay. Descriptive statistics were used to estimate seroprevalence, and a Chi-square test was employed to evaluate risk factors. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to assess associations between risk factors and seropositivity.
The herd-level seroprevalence was 66.67% (12/18), with a mean within-herd seroprevalence of 10.39% (95% CI: 7.21-13.57). The animal-level seroprevalence was 6.17% (41/665), with the highest rates observed in Bogor City (11.89%), followed by Bekasi (8.91%), East Jakarta (8.00%), and Tangerang (4.58%). Depok City had no positive cases in serum tests, though two cases were detected through milk ELISA. Mixed-species farms exhibited a significantly higher risk of infection than single-species farms (OR: 0.30, 95% CI: 0.14-0.66, p < 0.05). No significant difference was observed between goats and sheep (p > 0.05), nor between males and females (p = 0.84).
This study highlights a high seroprevalence of brucellosis in small ruminants within Jabodetabek, with mixed-species farming identified as a major risk factor. The findings underscore the need for enhanced surveillance, control measures, and public health interventions to mitigate disease transmission.
布鲁氏菌病由布鲁氏菌属引起，是一种具有重大公共卫生和经济意义的人畜共患病。在印度尼西亚，监测工作主要集中在牛布鲁氏菌病，尽管小型反刍动物作为疾病储存宿主起着关键作用，但关于它们的数据却很有限。本研究旨在估计印度尼西亚雅加达 - 茂物 - 德波 - 坦格朗 - 勿加泗地区山羊和绵羊布鲁氏菌病的血清阳性率，并确定与其传播相关的潜在风险因素。
于2023年5月至2023年11月进行了一项横断面研究，涉及雅加达、茂物、德波、坦格朗和勿加泗的18群山羊和绵羊。共采集了665份血样（355份来自山羊，310份来自绵羊）和112份乳样。使用玫瑰红试验、补体结合试验和酶联免疫吸附测定法对样本进行分析。采用描述性统计来估计血清阳性率，并使用卡方检验来评估风险因素。计算了具有95%置信区间（CI）的比值比（OR），以评估风险因素与血清阳性之间的关联。
畜群水平的血清阳性率为66.67%（12/18），畜群内平均血清阳性率为10.39%（95%CI：7.21 - 13.57）。动物水平的血清阳性率为6.17%（41/665），在茂物市观察到的阳性率最高（11.89%），其次是勿加泗（8.91%）、东雅加达（8.00%）和坦格朗（4.58%）。德波市血清检测无阳性病例，不过通过乳酶联免疫吸附测定法检测到2例。混养农场的感染风险显著高于单一物种农场（OR：0.30，95%CI：0.14 - 0.66，p < 0.05）。山羊和绵羊之间未观察到显著差异（p > 0.05），雄性和雌性之间也未观察到显著差异（p = 0.84）。
本研究突出了雅加达 - 茂物 - 德波 - 坦格朗 - 勿加泗地区小型反刍动物布鲁氏菌病的高血清阳性率，混养被确定为主要风险因素。研究结果强调需要加强监测、控制措施和公共卫生干预，以减轻疾病传播。
