Wang Jiule, Wang Teng, Han Rui, Shi Dongmei, Chen Biao
School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, China.
Central Laboratory, Jining key laboratory for the intelligent diagnosis of emerging infectious diseases, Jining, Shandong, China.
Cytojournal. 2025 Apr 19;22:45. doi: 10.25259/Cytojournal_272_2024. eCollection 2025.
The application of artificial intelligence (AI) in cancer pathology has shown significant potential to enhance diagnostic accuracy, streamline workflows, and support precision oncology. This review examines the current applications of AI across various cancer types, including breast, lung, prostate, and colorectal cancer, where AI aids in tissue classification, mutation detection, and prognostic predictions. The key technologies driving these advancements include machine learning, deep learning, and computer vision, which enable automated analysis of histopathological images and multi-modal data integration. Despite these promising developments, challenges persist, including ensuring data privacy, improving model interpretability, and meeting regulatory standards. Furthermore, this review explores future directions in AI-driven cancer pathology, including real-time diagnostics, explainable AI, and global accessibility, emphasizing the importance of collaboration between AI and pathologists. Addressing these challenges and leveraging AI's full potential could lead to a more efficient, equitable, and personalized approach to cancer care.
人工智能(AI)在癌症病理学中的应用已显示出显著潜力,可提高诊断准确性、简化工作流程并支持精准肿瘤学。本综述探讨了AI在各种癌症类型中的当前应用,包括乳腺癌、肺癌、前列腺癌和结直肠癌,其中AI有助于组织分类、突变检测和预后预测。推动这些进展的关键技术包括机器学习、深度学习和计算机视觉,它们能够对组织病理学图像进行自动分析并实现多模态数据整合。尽管有这些令人鼓舞的发展,但挑战依然存在,包括确保数据隐私、提高模型可解释性以及符合监管标准。此外,本综述还探讨了AI驱动的癌症病理学的未来方向,包括实时诊断、可解释AI和全球可及性,强调了AI与病理学家之间合作的重要性。应对这些挑战并充分发挥AI的潜力,可能会带来更高效、公平和个性化的癌症护理方法。