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心脏超声左心室分割的基础模型与特定领域模型

Foundation versus domain-specific models for left ventricular segmentation on cardiac ultrasound.

作者信息

Chao Chieh-Ju, Gu Yunqi Richard, Kumar Wasan, Xiang Tiange, Appari Lalith, Wu Justin, Farina Juan M, Wraith Rachael, Jeong Jiwoon, Arsanjani Reza, Kane Garvan C, Oh Jae K, Langlotz Curtis P, Banerjee Imon, Fei-Fei Li, Adeli Ehsan

机构信息

Department of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, MN, USA.

Stanford Institute for Human-Centered Artificial Intelligence, Stanford University, Stanford, CA, USA.

出版信息

NPJ Digit Med. 2025 Jun 6;8(1):341. doi: 10.1038/s41746-025-01730-y.

DOI:10.1038/s41746-025-01730-y
PMID:40481190
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12144204/
Abstract

The Segment Anything Model (SAM) was fine-tuned on the EchoNet-Dynamic dataset and evaluated on external transthoracic echocardiography (TTE) and Point-of-Care Ultrasound (POCUS) datasets from CAMUS (University Hospital of St Etienne) and Mayo Clinic (99 patients: 58 TTE, 41 POCUS). Fine-tuned SAM was superior or comparable to MedSAM. The fine-tuned SAM also outperformed EchoNet and U-Net models, demonstrating strong generalization, especially on apical 2-chamber (A2C) images (fine-tuned SAM vs. EchoNet: CAMUS-A2C: DSC 0.891 ± 0.040 vs. 0.752 ± 0.196, p < 0.0001) and POCUS (DSC 0.857 ± 0.047 vs. 0.667 ± 0.279, p < 0.0001). Additionally, SAM-enhanced workflow reduced annotation time by 50% (11.6 ± 4.5 sec vs. 5.7 ± 1.7 sec, p < 0.0001) while maintaining segmentation quality. We demonstrated an effective strategy for fine-tuning a vision foundation model for enhancing clinical workflow efficiency and supporting human-AI collaboration.

摘要

分割一切模型(SAM)在EchoNet-Dynamic数据集上进行了微调,并在来自圣艾蒂安大学医院(CAMUS)和梅奥诊所的外部经胸超声心动图(TTE)和床旁超声(POCUS)数据集上进行了评估(99例患者:58例TTE,41例POCUS)。微调后的SAM优于或可与MedSAM相媲美。微调后的SAM也优于EchoNet和U-Net模型,展现出强大的泛化能力,尤其是在心尖两腔(A2C)图像上(微调后的SAM与EchoNet对比:CAMUS-A2C:DSC为0.891±0.040,而EchoNet为0.752±0.196,p<0.0001)以及POCUS上(DSC为0.857±0.047,而EchoNet为0.667±0.279,p<0.0001)。此外,SAM增强的工作流程在保持分割质量的同时,将注释时间减少了50%(从11.6±4.5秒降至5.7±1.7秒,p<0.0001)。我们展示了一种有效的策略,用于微调视觉基础模型,以提高临床工作流程效率并支持人机协作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/576f/12144204/c476940cf8c0/41746_2025_1730_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/576f/12144204/5f2b7b8a7c5f/41746_2025_1730_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/576f/12144204/2ca24e4b2a59/41746_2025_1730_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/576f/12144204/c476940cf8c0/41746_2025_1730_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/576f/12144204/5f2b7b8a7c5f/41746_2025_1730_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/576f/12144204/2ca24e4b2a59/41746_2025_1730_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/576f/12144204/c476940cf8c0/41746_2025_1730_Fig3_HTML.jpg

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本文引用的文献

1
Medical SAM adapter: Adapting segment anything model for medical image segmentation.医学SAM适配器:将分割一切模型应用于医学图像分割
Med Image Anal. 2025 May;102:103547. doi: 10.1016/j.media.2025.103547. Epub 2025 Mar 19.
2
Metrics reloaded: recommendations for image analysis validation.重新加载指标:图像分析验证的建议。
Nat Methods. 2024 Feb;21(2):195-212. doi: 10.1038/s41592-023-02151-z. Epub 2024 Feb 12.
3
Segment anything in medical images.在医学图像中分割任何内容。
Nat Commun. 2024 Jan 22;15(1):654. doi: 10.1038/s41467-024-44824-z.
4
SDF4CHD: Generative Modeling of Cardiac Anatomies with Congenital Heart Defects.SDF4CHD:先天性心脏病心脏解剖结构的生成式建模
ArXiv. 2023 Nov 8:arXiv:2311.00332v2.
5
Segment anything model for medical image analysis: An experimental study.用于医学图像分析的分割模型:一项实验研究。
Med Image Anal. 2023 Oct;89:102918. doi: 10.1016/j.media.2023.102918. Epub 2023 Aug 2.
6
Point-of-Care Ultrasound (POCUS) as an Extension of the Physical Examination in Patients with Bacteremia or Candidemia.床旁超声(POCUS)作为菌血症或念珠菌血症患者体格检查的延伸
J Clin Med. 2022 Jun 23;11(13):3636. doi: 10.3390/jcm11133636.
7
The effectiveness of a blended POCUS curriculum on achieving basic focused bedside transthoracic echocardiography (TTE) proficiency. A formalized pilot study.混合式床边即时超声心动图(TTE)课程在实现基本重点床边经胸超声心动图(TTE)技能方面的效果。一项正式的试点研究。
Cardiovasc Ultrasound. 2021 Dec 9;19(1):39. doi: 10.1186/s12947-021-00268-9.
8
Automated interpretation of systolic and diastolic function on the echocardiogram: a multicohort study.超声心动图中收缩和舒张功能的自动解读:一项多队列研究。
Lancet Digit Health. 2022 Jan;4(1):e46-e54. doi: 10.1016/S2589-7500(21)00235-1. Epub 2021 Dec 1.
9
Artificial Intelligence for Automatic Measurement of Left Ventricular Strain in Echocardiography.人工智能在超声心动图中自动测量左心室应变。
JACC Cardiovasc Imaging. 2021 Oct;14(10):1918-1928. doi: 10.1016/j.jcmg.2021.04.018. Epub 2021 Jun 16.
10
Point-of-Care Ultrasound (POCUS) for the Cardiothoracic Anesthesiologist.即时超声心动图(POCUS)在心胸麻醉中的应用。
J Cardiothorac Vasc Anesth. 2022 Apr;36(4):1132-1147. doi: 10.1053/j.jvca.2021.01.018. Epub 2021 Jan 16.