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门诊环境中综合老年评估干预对老年人的有效性:一项系统评价/荟萃分析

The effectiveness of comprehensive geriatric assessment intervention for older people in outpatient setting: a systematic review / meta-analysis.

作者信息

Safitri Eka Dian, Ranakusuma Respati Wulansari, Siagian Natan Kevin Partogu, Marsigit Jessica, Saldi Siti Rizny Fitriana, Widyaningsih Widyaningsih, Istanti Rahmi, Azwar Muhammad Khifzhon, Siregar Risyad Abiyyu, Harimurti Kuntjoro, Setiati Siti

机构信息

Clinical Epidemiology and Evidence Based Medicine Unit dr. Cipto Mangunkusumo Hospital - Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.

Internal Medicine Department dr. Cipto Mangunkusumo Hospital-Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia.

出版信息

BMC Geriatr. 2025 Jun 9;25(1):418. doi: 10.1186/s12877-025-06048-8.

Abstract

INTRODUCTION

Comprehensive geriatric assessment (CGA) is a multidisciplinary diagnostic and treatment process that identifies a frail older person's medical, psychosocial, and functional limitations. The effectiveness of CGA in patients admitted to hospitals is well known, but it is still unclear whether those benefits translate to the outpatient setting. Therefore, this study aims to assess the effectiveness of CGA in the hospital outpatient setting.

METHODS

We collected randomized clinical trials comparing CGA and usual care in the outpatient setting for older patients (aged 60 years and above). We used a combination of the keywords and their synonyms in several databases: PubMed, EMBASE Proquest, and the clinical trial registry. Risk of bias (RoB) assessment was done using RoB 2 from Cochrane. GRADE assessment for outcome mortality and hospitalization was also done.

RESULT

We found seven articles with a total of 3,254 subjects undergoing CGA in the outpatient clinic. The implementation of CGA is highly varied from center to center. Low-quality evidence demonstrated that CGA did not significantly affect all-cause mortality, patient satisfaction, hospitalization, functional status of basic and instrumental activities of daily living, cognitive, and cost. Very low-quality evidence showed favorable quality of life in CGA group at 3 and 12 months, as reported by individual studies. No difference was found in all studies relating to the risk of hospitalization.

CONCLUSION

CGA is a complex intervention and is highly dependent on context. Therefore, a robust conclusion is challenging to make due to the different practices and measurement tools used in the studies. Further research using a guideline for hospital outpatient CGA may be beneficial.

摘要

引言

综合老年医学评估(CGA)是一个多学科的诊断和治疗过程,可识别体弱老年人的医学、心理社会和功能限制。CGA对住院患者的有效性是众所周知的,但这些益处是否能转化到门诊环境仍不清楚。因此,本研究旨在评估CGA在医院门诊环境中的有效性。

方法

我们收集了比较门诊环境中CGA与老年患者(60岁及以上)常规护理的随机临床试验。我们在几个数据库中使用了关键词及其同义词的组合:PubMed、EMBASE、Proquest和临床试验注册库。使用Cochrane的RoB 2进行偏倚风险(RoB)评估。还对结局死亡率和住院情况进行了GRADE评估。

结果

我们发现了7篇文章,共有3254名受试者在门诊接受CGA。CGA的实施在不同中心差异很大。低质量证据表明,CGA对全因死亡率、患者满意度、住院率、基本和工具性日常生活活动的功能状态、认知及成本均无显著影响。个别研究报告显示,极低质量证据表明CGA组在3个月和12个月时生活质量良好。在所有关于住院风险的研究中均未发现差异。

结论

CGA是一种复杂的干预措施,高度依赖于具体情况。因此,由于研究中使用的不同做法和测量工具,很难得出有力的结论。采用医院门诊CGA指南进行进一步研究可能会有所帮助。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/172a/12147235/99bf7f299db8/12877_2025_6048_Fig1_HTML.jpg

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