• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项病例对照研究,探究酒渣鼻患者与健康个体之间维生素D水平的差异。

A Case-Control Study Examining the Differences in Vitamin D Levels Between Individuals With Rosacea and Healthy Individuals.

作者信息

Faghihi Gita, Mohaghegh Fatemeh, Shoushtarizadeh Mohammad, Poostiyan Nazila, Hosseini Sayed Mohsen, Khosravi Arian

机构信息

Skin Diseases and Leishmaniasis Research Center, Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

J Cosmet Dermatol. 2025 Jun;24(6):e70141. doi: 10.1111/jocd.70141.

DOI:10.1111/jocd.70141
PMID:40492444
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12150255/
Abstract

BACKGROUND

Rosacea is an inflammatory and chronic skin condition that may be affected by many factors. The purpose of this study is to compare the level of vitamin D in two groups of cases (suffering from rosacea) and controls (healthy).

METHODS

This case-control study was conducted in 2022 on 62 patients referred to Sedigheh Tahereh dermatology clinic, Isfahan, Iran. The criteria for entering the case group are to have rosacea based on the updated phenotype-based diagnosis and classification system. Demographic variables such as age and gender as well as vitamin D levels were recorded for both case and control groups.

RESULTS

The mean of vitamin D level among patients with rosacea (29.9 ± 2.95) was higher than the control group (24.5 ± 2.14), but the difference was not statistically significant (p > 0.05). There was no significant difference in the mean of vitamin D level between rosacea patients and controls in gender or severity subgroups.

CONCLUSION

There is no significant difference in vitamin D levels between patients with rosacea and healthy individuals.

摘要

背景

酒渣鼻是一种炎症性慢性皮肤病,可能受多种因素影响。本研究的目的是比较两组病例(患有酒渣鼻)和对照组(健康)的维生素D水平。

方法

本病例对照研究于2022年对转诊至伊朗伊斯法罕Sedigheh Tahereh皮肤科诊所的62例患者进行。进入病例组的标准是根据最新的基于表型的诊断和分类系统患有酒渣鼻。记录病例组和对照组的年龄、性别等人口统计学变量以及维生素D水平。

结果

酒渣鼻患者的维生素D水平均值(29.9±2.95)高于对照组(24.5±2.14),但差异无统计学意义(p>0.05)。在性别或严重程度亚组中,酒渣鼻患者和对照组的维生素D水平均值无显著差异。

结论

酒渣鼻患者与健康个体的维生素D水平无显著差异。

相似文献

1
A Case-Control Study Examining the Differences in Vitamin D Levels Between Individuals With Rosacea and Healthy Individuals.一项病例对照研究,探究酒渣鼻患者与健康个体之间维生素D水平的差异。
J Cosmet Dermatol. 2025 Jun;24(6):e70141. doi: 10.1111/jocd.70141.
2
Vitamin D status in patients with rosacea.酒渣鼻患者的维生素D状况。
Cutan Ocul Toxicol. 2014 Mar;33(1):60-2. doi: 10.3109/15569527.2013.797907. Epub 2013 May 28.
3
Role of serum 25-hydroxyvitamin D levels and vitamin D receptor gene polymorphisms in patients with rosacea: a case-control study.血清 25-羟维生素 D 水平和维生素 D 受体基因多态性在酒渣鼻患者中的作用:一项病例对照研究。
Clin Exp Dermatol. 2019 Jun;44(4):397-403. doi: 10.1111/ced.13769. Epub 2018 Sep 23.
4
Can Hematologic Parameters be an Indicator of Metabolic Disorders Accompanying Rosacea?血液学参数能否作为酒渣鼻伴发代谢紊乱的指标?
Acta Dermatovenerol Croat. 2017 Jul;25(2):145-150.
5
Erythematotelangiectatic rosacea may be associated with a subclinical stage of demodicosis: a case-control study.红斑毛细血管扩张性酒渣鼻可能与毛囊蠕形螨的亚临床阶段有关:一项病例对照研究。
Br J Dermatol. 2019 Oct;181(4):818-825. doi: 10.1111/bjd.17817. Epub 2019 Mar 29.
6
The significance of Demodex folliculorum density in rosacea.毛囊蠕形螨密度在玫瑰痤疮中的意义。
Int J Dermatol. 1998 Jun;37(6):421-5. doi: 10.1046/j.1365-4362.1998.00218.x.
7
A Study on Vitamin D and Cathelicidin Status in Patients with Rosacea: Serum Level and Tissue Expression.酒渣鼻患者维生素D和杀菌肽状态的研究:血清水平与组织表达
Ann Dermatol. 2018 Apr;30(2):136-142. doi: 10.5021/ad.2018.30.2.136. Epub 2018 Feb 21.
8
Investigation of cognitive functions in patients with rosacea: a case-control study.酒渣鼻患者认知功能的调查:一项病例对照研究。
Arch Dermatol Res. 2025 Mar 28;317(1):644. doi: 10.1007/s00403-025-04173-3.
9
Hematological parameters as diagnostic biomarkers for patients with rosacea.用于诊断酒渣鼻患者的血液学参数。
J Dermatol. 2024 Jun;51(6):791-798. doi: 10.1111/1346-8138.17168. Epub 2024 Feb 29.
10
Vascular Remodeling in Rosacea: A Study on Microcirculatory Insights Using Oral Capillaroscopy.酒渣鼻的血管重塑:一项使用口腔毛细血管镜的微循环洞察研究。
J Cosmet Dermatol. 2025 Feb;24(2):e70012. doi: 10.1111/jocd.70012.

本文引用的文献

1
Vitamin D Status, Vitamin D Receptor Polymorphisms, and the Risk of Incident Rosacea: Insights from Mendelian Randomization and Cohort Study in the UK Biobank.维生素 D 状态、维生素 D 受体多态性与特发性红斑风险:来自英国生物库的孟德尔随机化和队列研究的见解。
Nutrients. 2023 Aug 30;15(17):3803. doi: 10.3390/nu15173803.
2
Rosacea: New Concepts in Classification and Treatment.酒渣鼻:分类和治疗的新概念。
Am J Clin Dermatol. 2021 Jul;22(4):457-465. doi: 10.1007/s40257-021-00595-7. Epub 2021 Mar 23.
3
Role of serum 25-hydroxyvitamin D levels and vitamin D receptor gene polymorphisms in patients with rosacea: a case-control study.血清 25-羟维生素 D 水平和维生素 D 受体基因多态性在酒渣鼻患者中的作用:一项病例对照研究。
Clin Exp Dermatol. 2019 Jun;44(4):397-403. doi: 10.1111/ced.13769. Epub 2018 Sep 23.
4
A Study on Vitamin D and Cathelicidin Status in Patients with Rosacea: Serum Level and Tissue Expression.酒渣鼻患者维生素D和杀菌肽状态的研究:血清水平与组织表达
Ann Dermatol. 2018 Apr;30(2):136-142. doi: 10.5021/ad.2018.30.2.136. Epub 2018 Feb 21.
5
Incidence and prevalence of rosacea: a systematic review and meta-analysis.酒渣鼻的发病率和患病率:系统评价和荟萃分析。
Br J Dermatol. 2018 Aug;179(2):282-289. doi: 10.1111/bjd.16481. Epub 2018 May 31.
6
Acne and Rosacea.痤疮与酒渣鼻。
Dermatol Ther (Heidelb). 2017 Jan;7(Suppl 1):43-52. doi: 10.1007/s13555-016-0168-8. Epub 2017 Feb 1.
7
Rosacea: part I. Introduction, categorization, histology, pathogenesis, and risk factors.酒渣鼻:第一部分。引言、分类、组织病理学、发病机制和危险因素。
J Am Acad Dermatol. 2015 May;72(5):749-58; quiz 759-60. doi: 10.1016/j.jaad.2014.08.028.
8
An evaluation of potential correlations between pathophysiologic mechanisms, clinical manifestations, and management of rosacea.酒渣鼻的病理生理机制、临床表现和治疗之间潜在相关性的评估。
Cutis. 2013 Mar;91(3 Suppl):1-8.
9
Vitamin D status in patients with rosacea.酒渣鼻患者的维生素D状况。
Cutan Ocul Toxicol. 2014 Mar;33(1):60-2. doi: 10.3109/15569527.2013.797907. Epub 2013 May 28.
10
Race, gender, class, and sexual orientation: intersecting axes of inequality and self-rated health in Canada.种族、性别、阶级和性取向:加拿大不平等和自评健康的交叉轴。
Int J Equity Health. 2011 Jan 17;10:3. doi: 10.1186/1475-9276-10-3.