Rostad S, Kleinschmidt-DeMasters B K, Manchester D K
Teratology. 1985 Oct;32(2):163-9. doi: 10.1002/tera.1420320203.
In this report we detail two congenital intracranial immature teratomas, noteworthy for their massive intracranial growth and extension through the skull with compromise of neck structures. Cytogenetic studies were done in both cases on the fetuses and their tumors and are the first in the literature. Few previously reported congenital intracranial teratomas have been described with neck extension. In both cases, polyhydramnios was detected by prenatal ultrasonography and was possibly caused by the laryngoesophageal and/or brainstem distortion by neoplasm. Possible reasons for such excessive, unchecked growth of teratomas in the fetal period are discussed.
在本报告中,我们详细介绍了两例先天性颅内未成熟畸胎瘤,其显著特点是在颅内大量生长并穿透颅骨,累及颈部结构。对这两例病例的胎儿及其肿瘤均进行了细胞遗传学研究,这在文献中尚属首次。此前报道的先天性颅内畸胎瘤很少有累及颈部的情况。在这两例病例中,产前超声检查均发现羊水过多,可能是由于肿瘤导致喉食管和/或脑干扭曲所致。本文还讨论了畸胎瘤在胎儿期过度、无节制生长的可能原因。