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2019冠状病毒病感染、症状严重程度、感知易感性与长期坚持保护行为之间的关联:洛杉矶大流行监测队列研究

Associations between COVID-19 infection, symptom severity, perceived susceptibility, and long-term adherence to protective behaviors: The Los Angeles pandemic surveillance cohort study.

作者信息

Lam Chun Nok, Kumar Nikhilesh, Herzig Shirin Emma, Unger Jennifer B, Sood Neeraj

机构信息

Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

Schaeffer Center for Health Policy and Economics, University of Southern California, Los Angeles, California, United States of America.

出版信息

PLoS One. 2025 Jun 12;20(6):e0326097. doi: 10.1371/journal.pone.0326097. eCollection 2025.

Abstract

BACKGROUND

During the COVID-19 pandemic, protective behaviors like mask wearing or social distancing were encouraged to limit viral spread. While pandemic fatigue is tied to the reduction of protective behaviors over time, little evidence exists examining predictors of long-term protective behaviors after recovering from COVID-19.

PURPOSE

This study investigates the association between COVID-19 infection status and future use of protective behaviors.

METHODS

We analyzed data from 676 adults who completed questionnaires in May 2021 and January 2023 as part of the Los Angeles Pandemic Surveillance Cohort Study. Measures included self-reported COVID-19 infection status and symptom severity, and mask wearing, hand washing, social distancing and perceived susceptibility to COVID-19. We performed Wilcoxon signed-rank tests, ordinal logit regression models, and mediation analysis to assess behavior change, associations, and whether perceived susceptibility mediated the effects.

RESULTS

The use of protective behaviors declined significantly from baseline to follow-up. Self- reported asymptomatic or mild COVID-19 infection was associated with less social distancing (aOR=0.57, 95% CI [0.35, 0.92]), less mask wearing (aOR=0.63, 95% CI [0.40, 0.99]), and lower perceived susceptibility (aβ = -0.17, 95% CI [-0.33, -0.02]) at follow-up. Moderate or severe COVID-19 infection was associated with less mask wearing (aOR=0.55, 95%CI [0.38, 0.81]). Perceived susceptibility to COVID-19 mediated 15% of the effect of mild COVID-19 infection on mask wearing (indirect effect aβ = -0.16, 95% CI [-0.31, -0.02]).

CONCLUSIONS

These results provide novel insights into the drivers of decreased use of protective behaviors over the course of the pandemic, particularly after an asymptomatic or mild COVID-19 infection. More research is needed on the effect of COVID-19 infection on long-term adherence to preventive measures against future pandemics.

摘要

背景

在新冠疫情期间,人们被鼓励采取如佩戴口罩或保持社交距离等防护行为以限制病毒传播。虽然疫情疲劳与防护行为随时间减少有关,但几乎没有证据研究新冠康复后长期防护行为的预测因素。

目的

本研究调查新冠感染状况与未来防护行为使用之间的关联。

方法

我们分析了来自676名成年人的数据,这些人作为洛杉矶疫情监测队列研究的一部分,于2021年5月和2023年1月完成了问卷调查。测量指标包括自我报告的新冠感染状况和症状严重程度,以及佩戴口罩、洗手、保持社交距离和对新冠的易感性认知。我们进行了Wilcoxon符号秩检验、有序logit回归模型和中介分析,以评估行为变化、关联,以及易感性认知是否介导了这些影响。

结果

从基线到随访,防护行为的使用显著下降。自我报告无症状或轻症新冠感染与随访时较少的社交距离(调整后比值比[aOR]=0.57,95%置信区间[CI][0.35, 0.92])、较少的口罩佩戴(aOR=0.63,95%CI[0.40, 0.99])以及较低的易感性认知(调整后β=-0.17,95%CI[-0.33, -0.02])相关。中度或重度新冠感染与较少的口罩佩戴(aOR=0.55,95%CI[0.38, 0.81])相关。对新冠的易感性认知介导了轻症新冠感染对口罩佩戴影响的15%(间接效应调整后β=-0.16,95%CI[-0.31, -0.02])。

结论

这些结果为疫情期间防护行为使用减少的驱动因素提供了新的见解,特别是在无症状或轻症新冠感染之后。关于新冠感染对未来大流行预防措施长期依从性的影响,还需要更多研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d2b/12161579/3183d53b640d/pone.0326097.g001.jpg

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