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头盔式呼吸器对实验动物过敏(LAA)所致职业性哮喘的疗效。

Efficacy of the helmet respirator in occupational asthma due to laboratory animal allergy (LAA).

作者信息

Slovak A J, Orr R G, Teasdale E L

出版信息

Am Ind Hyg Assoc J. 1985 Aug;46(8):411-5. doi: 10.1080/15298668591395085.

DOI:10.1080/15298668591395085
PMID:4050677
Abstract

The efficacy of the Racal Airstream helmet respirator in preventing symptoms due to Laboratory Animal Allergy (LAA) was assessed in ten patients. Eight of these were established cases of asthma and two had severe rhinitis. Peak expiratory flow rate (PEFR) readings, recorded every two hours, were kept for seven weeks (six in exposure), together with a diary of subjective symptoms. Objective evidence of good protection was obtained in six out of the eight asthmatic patients; overt asthma was seen in the other two. The helmet respirator would appear to be a valuable adjunct in the management of occupational asthma in those who opt to remain in exposure. Those asthmatics who use a helmet respirator need to be monitored carefully and regularly to ensure that their respiratory function has not deteriorated. Persons with severe local symptoms of rhinitis and conjunctivitis also benefit subjectively from the use of the helmet although symptoms are not completely suppressed nor may progression towards asthma be prevented. The findings may well be applicable to the management of other types of occupational asthma but any inferences should be drawn with caution.

摘要

对10名患者评估了Racal气流头盔式呼吸器在预防实验动物过敏(LAA)所致症状方面的疗效。其中8例为确诊哮喘病例,2例患有严重鼻炎。每两小时记录一次的呼气峰值流速(PEFR)读数持续记录7周(暴露期6周),同时记录主观症状日记。8例哮喘患者中有6例获得了良好防护的客观证据;另外2例出现了明显哮喘。对于那些选择继续暴露的人来说,头盔式呼吸器似乎是职业性哮喘管理中的一种有价值的辅助设备。使用头盔式呼吸器的哮喘患者需要仔细且定期地进行监测,以确保其呼吸功能没有恶化。患有严重鼻炎和结膜炎局部症状的人使用头盔也能主观上受益,尽管症状不能完全消除,也无法预防向哮喘的进展。这些发现很可能适用于其他类型职业性哮喘的管理,但任何推断都应谨慎得出。

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