Evaluation of occupational exposure to carbon disulphide by blood, exhaled air, and urine analysis.

This paper compares three analytical methods that may be considered for monitoring workers who are exposed to carbon disulphide (CS2). An estimate of the uptake of CS2 was assessed by the measurement of "bound" CS2 in blood, CS2 in expired alveolar air, and 2-thiothiazolidine-4-carboxylic acid (TTCA) in urine. The concentration of TTCA in end-of-shift urine samples was related to exposure and appears to be a good measure of uptake of CS2.