Jiao Yuan, Miao Xuewen, Wang Lizhang, Hong Shasha, Gao Yifang, Wang Xin
School of Environment and Spatial Informatics, China University of Mining and Technology, Xuzhou 221116, China.
Wanli Energy Technology Development Co., Ltd., Zhejiang Wanli University, Ningbo 315100, China.
Materials (Basel). 2025 Jun 5;18(11):2669. doi: 10.3390/ma18112669.
Flavonoid alcohols, particularly quercetin, as emerging antioxidants, demand advanced detection methodologies to comprehensively explore and evaluate their potential environmental and health risks. In this study, nitrogen-chlorine co-doped carbon dots (N, Cl-CDs), featuring an extended wavelength emission at 625 nm, were synthesized via the reaction of 4-chloro-1,2-phenylenediamine with polyethyleneimine. The engineered N, Cl-CDs exhibit superior photostability, exceptional aqueous dispersibility, and anti-interference capability in complex matrices. Leveraging static electron transfer mechanisms, the N, Cl-CDs demonstrate selective fluorescence quenching toward quercetin with an ultralow detection limit of 60.42 nM. Validation through rigorous spiked recovery assays in apple peel and red wine has been proficiently performed with satisfactory accuracy, highlighting the significant prospect of the constructed N, Cl-CDs for quercetin identification in real samples. This study provides valuable insights into the analytical determination of flavonoid compounds in complex environmental matrices, highlighting the potential of N, Cl-CDs for environmental and food safety monitoring.
类黄酮醇，尤其是槲皮素，作为新兴的抗氧化剂，需要先进的检测方法来全面探索和评估其潜在的环境和健康风险。在本研究中，通过4-氯-1,2-苯二胺与聚乙烯亚胺反应合成了在625 nm处具有长波长发射的氮氯共掺杂碳点（N, Cl-CDs）。所制备的N, Cl-CDs在复杂基质中表现出优异的光稳定性、出色的水分散性和抗干扰能力。利用静态电子转移机制，N, Cl-CDs对槲皮素表现出选择性荧光猝灭，超低检测限为60.42 nM。通过在苹果皮和红酒中进行严格的加标回收率测定进行了验证，结果准确度令人满意，突出了所构建的N, Cl-CDs在实际样品中鉴定槲皮素的巨大前景。本研究为复杂环境基质中类黄酮化合物的分析测定提供了有价值的见解，突出了N, Cl-CDs在环境和食品安全监测方面的潜力。
