各种根管封闭剂对……的抗菌效果
Antibacterial Efficacy of Various Root Canal Sealers Against .
作者信息
Das Maneesha, Joshi Prachi, Jariwala Arpita Hasmukhlal, Patil Sheetal Shivaji, Singh Aditi, Jena Debkant
机构信息
Professor and Head-in-Charge, Department of Conservative Dentistry and Endodontics, Institute of Dental Sciences, Siksha 'O' Anusandhan Deemed to be University, Bhubaneswar, Odisha, India.
Professor, Department of Conservative Dentistry and Endodontics, Ajeenkya D.Y.Patil Dental School, Pune, Maharashtra, India.
出版信息
J Pharm Bioallied Sci. 2025 May;17(Suppl 1):S269-S271. doi: 10.4103/jpbs.jpbs_675_25. Epub 2025 Apr 29.
OBJECTIVE
The objective of this study is to evaluate and compare the antibacterial effectiveness of different root canal sealers against .
MATERIALS AND METHODS
The antibacterial efficacy of four root canal sealers-three bioceramic materials (TotalFill Bioceramic Sealer, BioRoot Root Canal Sealer, and MTA Fillapex) and one epoxy resin-based sealer (AH Plus)-against (ATCC 29212) was assessed using a modified direct contact test. Every sealer was made under the manufacturer's instructions, and its antibacterial activity was evaluated against newly mixed and set sealers (1 and 3 days) at various intervals (2, 5, 20, and 60 min). agar was used to plate the bacterial suspension, and one-way ANOVA was used for statistical analysis.
RESULTS
TotalFill Bioceramic Sealer showed the highest antibacterial efficacy, followed by BioRoot Root Canal Sealer, MTA Fillapex, and AH Plus.
CONCLUSION
Bioceramic root canal sealers, particularly TotalFill, demonstrate superior antibacterial efficacy against compared to epoxy resin-based sealers such as AH Plus.
目的
本研究的目的是评估和比较不同根管封闭剂的抗菌效果。
材料与方法
使用改良直接接触试验评估四种根管封闭剂——三种生物陶瓷材料（TotalFill生物陶瓷封闭剂、BioRoot根管封闭剂和MTA Fillapex）和一种环氧树脂基封闭剂（AH Plus）对粪肠球菌（ATCC 29212）的抗菌效果。每种封闭剂均按照制造商的说明制备，并在不同时间间隔（2、5、20和60分钟）对新混合和凝固的封闭剂（1天和3天）评估其抗菌活性。使用琼脂平板接种细菌悬液，并采用单因素方差分析进行统计分析。
结果
TotalFill生物陶瓷封闭剂显示出最高的抗菌效果，其次是BioRoot根管封闭剂、MTA Fillapex和AH Plus。
结论
与AH Plus等环氧树脂基封闭剂相比，生物陶瓷根管封闭剂，尤其是TotalFill，对粪肠球菌显示出卓越的抗菌效果。
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