Hegrenaes L, Hatle L
Br Heart J. 1985 Oct;54(4):396-404. doi: 10.1136/hrt.54.4.396.
The peak and mean aortic transvalvar pressure differences measured invasively and non-invasively by continuous wave Doppler echocardiography were compared in 87 consecutive patients with aortic stenosis. The mean values were calculated from the maximal velocities of the aortic jet recorded with a spectral display of the Doppler frequency shifts and by applying a modified Bernoulli equation. Technically satisfactory velocity curves for estimating the mean pressure differences could not be obtained in three patients and invasive measurements were not obtained in two. In all patients the peak transvalvar pressure difference was calculated since the aortic jet was identified non-invasively. The peak and mean pressure differences measured invasively and non-invasively correlated well--with only minor underestimation of the pressure differences measured with the Doppler technique--regardless of age, sex, and the presence or absence of aortic valvar regurgitation, or other valvar lesions. With a systematic search for the highest velocities in the aortic jet and with on line spectral analysis of the Doppler frequencies the peak and the mean aortic pressure differences can be determined non-invasively with a high degree of precision in almost all patients.
采用连续波多普勒超声心动图对87例连续性主动脉瓣狭窄患者进行有创和无创测量，比较主动脉跨瓣压差的峰值和平均值。平均值通过多普勒频移频谱显示记录的主动脉射流最大速度并应用改良的伯努利方程计算得出。3例患者未能获得技术上满意的用于估计平均压差的速度曲线，2例未进行有创测量。在所有患者中，由于通过无创方法识别了主动脉射流，因此计算了跨瓣压差峰值。无论年龄、性别、有无主动脉瓣反流或其他瓣膜病变，有创和无创测量的峰值和平均压差相关性良好，仅多普勒技术测量的压差略有低估。通过系统寻找主动脉射流中的最高速度并对多普勒频率进行在线频谱分析，几乎所有患者都能以高度的精确性无创测定主动脉压差的峰值和平均值。
