Rudnyckyj Stanislav, Thomsen Mette Hedegaard
Department of Energy, Aalborg University, Esbjerg, Denmark.
Probiotics Antimicrob Proteins. 2025 Jun 17. doi: 10.1007/s12602-025-10617-z.
The growing demand for the sustainable and cost-effective production of probiotics and postbiotics has highlighted the potential of saline and marine plants as novel substrates. These plants, including seaweeds and halophytes, are abundant and nutrient-rich and require minimal resources, making them ideal candidates for green biorefineries. The incorporation of saline plant-based feedstocks could lower media costs and environmental impact, as these plants do not require arable land or freshwater while contributing to carbon sequestration and sustainable farming. The development of integrated biorefineries could drive economic feasibility by facilitating cost-effective probiotic and postbiotic production. However, challenges such as high salt content and lignocellulosic composition may complicate microbial fermentation. This review examines recent advancements in leveraging naturally salt-tolerant probiotics and efficient bioconversion methods to address these challenges. It explores the nutritional profiles of saline plants, their prebiotic potential, and their synergetic compatibility with diverse probiotic strains, including probiotic bacteria and fungi and their metabolites. Additionally, the review discusses state-of-the-art fermentation techniques tailored to saline plant-based substrates and the possible advantages of saline feedstocks for probiotics and postbiotics production through biorefinery pathways. The work highlights the transformative potential of saline and marine plant-derived probiotics and postbiotics in health supplementation and biotechnological innovation, contributing to biorefinery development within a circular economy framework.
对益生菌和后生元可持续且经济高效生产的需求不断增长，凸显了盐生植物和海洋植物作为新型底物的潜力。这些植物，包括海藻和盐生植物，数量丰富且营养丰富，所需资源极少，使其成为绿色生物精炼厂的理想候选者。采用基于盐生植物的原料可以降低培养基成本和环境影响，因为这些植物不需要耕地或淡水，同时有助于碳固存和可持续农业。综合生物精炼厂的发展可以通过促进具有成本效益的益生菌和后生元生产来推动经济可行性。然而，高盐含量和木质纤维素组成等挑战可能会使微生物发酵变得复杂。本综述探讨了利用天然耐盐益生菌和高效生物转化方法应对这些挑战的最新进展。它研究了盐生植物的营养成分、它们的益生元潜力，以及它们与各种益生菌菌株（包括益生菌细菌和真菌及其代谢产物）的协同兼容性。此外，该综述还讨论了针对基于盐生植物的底物量身定制的先进发酵技术，以及通过生物精炼途径生产益生菌和后生元时盐生原料可能具有的优势。这项工作突出了盐生植物和海洋植物衍生的益生菌和后生元在健康补充和生物技术创新方面的变革潜力，为循环经济框架内的生物精炼厂发展做出贡献。
