Arjmandmazidi Shiva, Heidari Hamid Reza, Ghasemnejad Tohid, Mori Zeinab, Molavi Leila, Meraji Amir, Kaghazchi Shadi, Mehdizadeh Aghdam Elnaz, Montazersaheb Soheila
Molecular Medicine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tabriz University of Medical, Sciences, Tabriz, Iran.
J Transl Med. 2025 Jun 18;23(1):678. doi: 10.1186/s12967-025-06488-1.
Artificial Intelligence (AI) offers a revolutionary approach to improve decision-making in medicine through the use of advanced computational tools. Its ability to analyze large and complex datasets enables a thorough evaluation of multiple factors, leading to a deeper understanding of medical procedures. Numerous studies have demonstrated that AI has made significant advancements in areas such as organ allocation, donor-recipient matching, and immunosuppression protocols in organ transplantation. The transplantation process consists of three key stages: pre-transplant evaluation, the surgical procedure, and post-transplant management. AI can enhance all three stages by analyzing and integrating data from histopathological reports, lab results, radiological features, and patient demographics to aid in matching donors and recipients. Additionally, AI supports robotic-assisted surgery and optimizes post-transplant regimens while evaluating complications. Various researches have utilized machine learning (ML) to predict medication bioavailability immediately after transplantation and assess the risk of post-transplant complications based on factors like genetic phenotypes, age, gender, and body mass index. This review aims to gather information on AI applications across various stages of organ transplantation and elaborate the strategies and tools relevant to these processes.
人工智能(AI)提供了一种革命性的方法,通过使用先进的计算工具来改善医学决策。它分析大型复杂数据集的能力使得能够对多个因素进行全面评估,从而更深入地理解医疗程序。众多研究表明,人工智能在器官分配、供体-受体匹配以及器官移植中的免疫抑制方案等领域取得了重大进展。移植过程包括三个关键阶段:移植前评估、手术过程和移植后管理。人工智能可以通过分析和整合组织病理学报告、实验室结果、放射学特征和患者人口统计学数据来增强这三个阶段,以帮助匹配供体和受体。此外,人工智能支持机器人辅助手术,并在评估并发症的同时优化移植后治疗方案。各种研究利用机器学习(ML)来预测移植后立即出现的药物生物利用度,并根据遗传表型、年龄、性别和体重指数等因素评估移植后并发症的风险。本综述旨在收集有关人工智能在器官移植各个阶段应用的信息,并阐述与这些过程相关的策略和工具。