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临床确诊多发性硬化症中的图形视觉诱发电位和闪光视网膜电图

Pattern visual evoked potentials and flash electroretinogram in clinically definite multiple sclerosis.

作者信息

Pierelli F, Pozzessere G, Stefano E, Martelli M, Rizzo P A, Morocutti C

出版信息

Eur Neurol. 1985;24(5):324-9. doi: 10.1159/000115819.

DOI:10.1159/000115819
PMID:4054182
Abstract

The authors have studied, by means of pattern visual evoked potential (VEP) and flash electroretinogram (ERG) recordings, a group of 15 patients affected by definite multiple sclerosis. All of the subjects examined presented a clinical history indicating involvement of the visual pathways; VEPs were altered in a high percentage of eyes examined (93.3%), while a lower percentage of abnormal ERGs was seen (20% of eyes examined). The only type of ERG alteration found consisted of a pathologic b wave voltage increase, observed mainly with red flash stimuli. This finding could be attributed to an involvement of centrifugal optic nerve fibers having inhibitory functions on retinal cells.

摘要

作者通过图形视觉诱发电位(VEP)和闪光视网膜电图(ERG)记录,对一组15例确诊为多发性硬化症的患者进行了研究。所有接受检查的受试者都有提示视觉通路受累的临床病史;在检查的高比例眼睛中(93.3%)VEP发生改变,而ERG异常的比例较低(检查眼睛的20%)。发现的唯一一种ERG改变是病理性b波电压升高,主要在红色闪光刺激时观察到。这一发现可能归因于对视网膜细胞具有抑制功能的离心视神经纤维受累。

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