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本文引用的文献

1
Gut hormone responses in the irritable bowel syndrome.肠易激综合征中的肠道激素反应。
Digestion. 1981;21(4):219-24. doi: 10.1159/000198566.
2
Gut hormone release after intestinal resection.肠道切除术后肠道激素的释放
Gut. 1982 Oct;23(10):854-61. doi: 10.1136/gut.23.10.854.
3
Effect of motilin on the gastric emptying of glucose and fat in humans.胃动素对人体葡萄糖和脂肪胃排空的影响。
Gastroenterology. 1981 Mar;80(3):456-60.
4
Decreased plasma motilin concentrations in pregnancy.孕期血浆胃动素浓度降低。
Br Med J (Clin Res Ed). 1982 Nov 20;285(6353):1453-4. doi: 10.1136/bmj.285.6353.1453.
5
Colonic inhibition of gastric secretion in man.人体结肠对胃酸分泌的抑制作用。
Dig Dis Sci. 1981 Mar;26(3):195-201. doi: 10.1007/BF01391629.
6
Gut hormones in acute diarrhoea.急性腹泻中的肠道激素
Gut. 1983 Jul;24(7):665-71. doi: 10.1136/gut.24.7.665.
7
Effect of irritant purgatives on the myenteric plexus in man and the mouse.刺激性泻药对人和小鼠肌间神经丛的作用。
Gut. 1968 Apr;9(2):139-43. doi: 10.1136/gut.9.2.139.
8
A ne method for studying gut transit times using radioopaque markers.一种使用不透射线标记物研究肠道通过时间的新方法。
Gut. 1969 Oct;10(10):842-7. doi: 10.1136/gut.10.10.842.
9
Towards a radiologic definition of idiopathic megacolon.迈向特发性巨结肠的放射学定义。
Gastrointest Radiol. 1985;10(2):167-9. doi: 10.1007/BF01893094.
10
Post prandial changes in colonic motility related to serum gastrin levels.与血清胃泌素水平相关的餐后结肠动力变化。
Scand J Gastroenterol. 1976;11(2):145-9.

功能性肠病中症状与循环中胃动素、胰多肽和胃泌素浓度之间的正相关关系。

Positive correlation between symptoms and circulating motilin, pancreatic polypeptide and gastrin concentrations in functional bowel disorders.

作者信息

Preston D M, Adrian T E, Christofides N D, Lennard-Jones J E, Bloom S R

出版信息

Gut. 1985 Oct;26(10):1059-64. doi: 10.1136/gut.26.10.1059.

DOI:10.1136/gut.26.10.1059
PMID:4054704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1432940/
Abstract

Motilin, pancreatic polypeptide and gastrin blood concentrations in response to drinking water have been studied in 40 patients with functional bowel disease and compared with results in two groups of healthy control subjects. Patients with slow transit constipation and idiopathic megacolon showed impaired motilin release. Pancreatic polypeptide release was reduced in patients with slow transit constipation, but increased in those with functional diarrhoea. Gastrin release was impaired in all groups complaining of chronic constipation. Circulating motilin, pancreatic polypeptide and gastrin concentrations appear to bear some relationship to intestinal transit time in patients with functional bowel disorders.

摘要

对40例功能性肠病患者饮用后胃动素、胰多肽和胃泌素的血药浓度进行了研究，并与两组健康对照者的结果进行了比较。慢传输型便秘和特发性巨结肠患者的胃动素释放受损。慢传输型便秘患者的胰多肽释放减少，但功能性腹泻患者的胰多肽释放增加。所有主诉慢性便秘的患者胃泌素释放均受损。在功能性肠病患者中，循环中的胃动素、胰多肽和胃泌素浓度似乎与肠道转运时间存在一定关系。