尼日利亚埃努古市两家医院献血者中疟原虫的流行情况。

Prevalence of malaria parasites among blood donors in two hospitals in Enugu metropolis, Nigeria.

作者信息

Aluh Samuel ThankGod, Ubachukwu Patience Obiageli, Onah Kyrian Ikenna, Oladepo Gabriel Adebayo, Ukwen Chidi Ole, Rimamkirnde Fupsin

机构信息

Parasitology and Public Health Unit, Department of Zoology and Environmental Biology, University of Nigeria, Nsukka, Nigeria.

出版信息

Hematol Transfus Cell Ther. 2025 Jun 18;47(3):103858. doi: 10.1016/j.htct.2025.103858.

DOI:10.1016/j.htct.2025.103858

PMID:40554394

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12214262/

Abstract

INTRODUCTION

Screening of blood donors for malaria parasites as recommended by the World Health Organization (WHO) is currently not included in the protocols and procedures for pre-screening blood donors of many private and public health facilities in Nigeria.

METHODS

A cross-sectional study was conducted of voluntary, family, and remunerated blood donors in two hospitals in the Enugu metropolis. A well-structured questionnaire was used to collect demographics and blood donation history data. Five milliliters of blood were collected from each blood donor, of which 2 mL were used to screen for malaria parasites.

RESULTS

Three hundred and seventy-seven blood donors participated in the study with 148 (39.3 %) being malaria-positive. Most of the blood donors were in the age groups 16-25 and 26-35 years old with prevalences of 40.0 % and 44.1 %, respectively. The prevalence of malaria in both age groups was high compared to the 36-45 years age group (26.7 %). Still, the overall difference in malaria prevalence across the four age groups was not statistically significant (χ = 5.437; p-value = 0.142). The majority (n = 290; 76.9 %) of the donors were male, while 87 (23.1 %) were female. Although female blood donors had a higher prevalence of malaria (47.1 %) compared to male donors (36.9 %), the difference was not statistically significant (p-value = 0.057).

CONCLUSION

The high prevalence of malaria in the studied area, suggests the need for careful screening of blood samples of blood donors for malaria parasites.

摘要

引言

按照世界卫生组织（WHO）的建议，对献血者进行疟原虫筛查目前未纳入尼日利亚许多私立和公立医疗机构献血者预检的方案和程序中。

方法

在埃努古市的两家医院对自愿、家庭和有偿献血者进行了一项横断面研究。使用一份结构完善的问卷收集人口统计学和献血历史数据。从每位献血者采集5毫升血液，其中2毫升用于筛查疟原虫。

结果

377名献血者参与了该研究，其中148人（39.3%）疟原虫检测呈阳性。大多数献血者年龄在16 - 25岁和26 - 35岁组，患病率分别为40.0%和44.1%。与36 - 45岁年龄组（26.7%）相比，这两个年龄组的疟疾患病率都较高。然而，四个年龄组疟疾患病率的总体差异无统计学意义（χ = 5.437；p值 = 0.142）。大多数（n = 290；76.9%）献血者为男性，而87人（23.1%）为女性。尽管女性献血者的疟疾患病率（47.1%）高于男性献血者（36.9%），但差异无统计学意义（p值 = 0.057）。