Pereira Natalia Stefany, Fabbri Camila, Moya Kemily Nunes, Ferreira Ana Carolina Monteiro, Andrade Francy's Sayara, Santana Rosa Amélia, Ríos-Velásquez Claudia Maria, Aquino Priscila Ferreira de, Lopes Stefanie Costa Pinto
Instituto Leônidas & Maria Deane, Fiocruz Amazônia, Manaus 69057-070, AM, Brazil.
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado, Manaus 69040-000, AM, Brazil.
J Fungi (Basel). 2025 Jun 18;11(6):464. doi: 10.3390/jof11060464.
Malaria remains a public health issue across the world. Different methods have been analyzed to achieve this disease's elimination, such as the vector control of spp. Control strategies include the use of different classes of insecticides, although the accelerated evolution of vectors resistant to them makes the development of alternative control methods necessary. Therefore, entomopathogenic fungi have been considered to be promising biopesticides, given that they are safe for human beings and the environment. This study aimed to evaluate the entomopathogenic activity of fungi collected in the Amazon Rainforest against adult female mosquitoes. Females were exposed to four different species of fungi and observed daily to evaluate their survival rate. Also, fungi species' behavior was analyzed through scanning electron microscopy (SEM). Those exposed to and had their survival rate reduced. SEM confirmed the development of fungi on the mosquitoes after 48 h. The findings suggest that the entomopathogenic potential of the fungi used in this study should be considered, given the reduction in the survival rate of mosquitoes.
疟疾仍然是一个全球性的公共卫生问题。人们已经分析了不同的方法来实现消除这种疾病的目标，比如对疟蚊属物种的病媒控制。控制策略包括使用不同种类的杀虫剂，尽管对杀虫剂产生抗性的病媒加速进化使得有必要开发替代控制方法。因此，昆虫病原真菌被认为是有前景的生物杀虫剂，因为它们对人类和环境都是安全的。本研究旨在评估从亚马逊雨林采集的真菌对成年雌性疟蚊的昆虫病原活性。将雌性疟蚊暴露于四种不同的真菌物种，并每天观察以评估它们的存活率。此外，通过扫描电子显微镜（SEM）分析真菌物种的行为。暴露于[具体真菌名称1]和[具体真菌名称2]的疟蚊存活率降低。扫描电子显微镜证实了48小时后真菌在疟蚊身上的生长。研究结果表明，鉴于疟蚊存活率的降低，应考虑本研究中所用真菌的昆虫病原潜力。
