Suppr超能文献

采用自制水果烈酒生产新方法是否能降低消费者健康风险?

Does Embracing New Approaches in Homemade Fruit Spirit Production Lessen Consumer Health Risks?

作者信息

Bijelić Katarina, Torović Ljilja, Milijašević Boris, Kladar Nebojša, Stilinović Nebojša, Srđenović Čonić Branislava

机构信息

Department of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.

Center for Medical and Pharmaceutical Investigations and Quality Control, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.

出版信息

Toxics. 2025 May 28;13(6):444. doi: 10.3390/toxics13060444.

Abstract

Fruit spirits have roots in traditions across Eastern and Central Europe. Homemade/unrecorded spirits are typically produced under inconsistent conditions, leading to inconsistent product quality. From the safety aspect, great concentration variability of exclusively harmful substances (methanol and acetaldehyde) and compounds with either favorable or hazardous properties (ethyl acetate and higher alcohols), depending on their amount, must be considered. An option to ensure their safety could be a dephlegmator, a central component in column distillation systems. To determine whether such an approach in small-scale spirit production lessens the health risks from harmful volatile compounds, 35 fruit spirits were investigated using HSS-GC-FID. Dephlegmator usage was associated with lower median methanol concentrations (1878 vs. 3723 mg/L p.a.) and a narrower concentration span. The remaining analytes showed no significant reduction in median level; however, the ranges have narrowed. A risk assessment (margin of exposure approach) revealed that dephlegmator usage increased the proportion of methanol-safe samples. The risk of acetaldehyde was equivalent or somewhat greater in the dephlegmator spirit group, suggesting challenges for optimizing the head cut during distillation. Ethyl acetate and higher alcohols did not pose a risk regardless of dephlegmator use. These findings support dephlegmator usage as a useful but insufficient intervention in home/small-scale spirit production to obtain safer products of consistent quality.

摘要

水果烈酒在东欧和中欧的传统中有着根源。自制/未记录的烈酒通常在不一致的条件下生产,导致产品质量不稳定。从安全角度来看,必须考虑仅有害物质(甲醇和乙醛)以及具有有利或有害特性的化合物(乙酸乙酯和高级醇)的高度浓度变异性,这取决于它们的含量。确保其安全的一个选择可能是分馏器,它是柱式蒸馏系统的核心组件。为了确定小规模烈酒生产中的这种方法是否能降低有害挥发性化合物带来的健康风险,使用高速气相色谱-火焰离子化检测器(HSS-GC-FID)对35种水果烈酒进行了研究。使用分馏器与较低的甲醇中位数浓度(每年1878毫克/升对3723毫克/升,p.a.)以及更窄的浓度范围相关。其余分析物的中位数水平没有显著降低;然而,范围变窄了。风险评估(暴露边际方法)表明,使用分馏器增加了甲醇安全样品的比例。在使用分馏器的烈酒组中,乙醛的风险相当或略高,这表明在蒸馏过程中优化初馏物截取存在挑战。无论是否使用分馏器,乙酸乙酯和高级醇都不会构成风险。这些发现支持将使用分馏器作为家庭/小规模烈酒生产中一种有用但并不充分的干预措施,以获得质量一致的更安全产品。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91c1/12197528/d184c28c7106/toxics-13-00444-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验