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克罗地亚全科医生开具抗糖尿病药物的真实横断面研究

Prescribing Antidiabetic Medications Among GPs in Croatia-A Real-Life Cross-Sectional Study.

作者信息

Kurevija Tomislav, Schönberger Ema, Matić Ličanin Matea, Bilić-Ćurčić Ines, Trtica-Majnarić Ljiljana, Canecki-Varžić Silvija

机构信息

Faculty of Medicine, J.J. Strossmayer University of Osijek, 31000 Osijek, Croatia.

Health Center of Osijek-Baranja County, 31000 Osijek, Croatia.

出版信息

Biomedicines. 2025 Jun 17;13(6):1491. doi: 10.3390/biomedicines13061491.

DOI:10.3390/biomedicines13061491
PMID:40564210
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12190737/
Abstract

: Advances in the treatment of type 2 diabetes (T2D) in recent decades have been primarily focused on its broader understanding in the context of the possibility of preventing the development and progression of the disease and of cardiovascular (CV) complications. Nevertheless, worldwide research indicates that individuals with T2D are still under-regulated, both in terms of glycemic control and in preventing CV complications. The aim of this study was to examine Croatian general practitioners (GPs)' practice and patterns in prescribing antidiabetic medications and their understanding of guidelines. : Research was conducted using a self-designed anonymous survey, which was delivered to the e-mail addresses of GPs throughout Croatia in digital format. Respondents were solely GPs, without any restrictions with regard to their characteristics. Data on the number of individuals diagnosed with T2D and prescribed a specific medication were based on declarations by respondents from their e-health records. : Approximately 59% of individuals with T2D are cared for solely by GPs. In terms of achieving targeted values of HbA1c, 47% of individuals with T2D are well regulated. Almost all the respondents claim that they review prescribed T2D therapy at least once a year. A total of 47.6% of respondents have read and entirely understood the EASD/ADA guidelines, but 58.3% apply the dual principles of controlling HbA1c levels and CV risk in the treatment of T2D. In individuals with associated CV comorbidity, SGLT2ins were the most frequently prescribed. : The results indicate that Croatian GPs are still inclined to apply outdated paradigms of T2D treatment but that they are gradually accepting new regimens of care and recommendations for prescribing novel, more effective medications.

摘要

近几十年来,2型糖尿病(T2D)治疗方面的进展主要集中在更全面地了解该疾病及其预防疾病发展和进展以及心血管(CV)并发症的可能性。然而,全球研究表明,T2D患者在血糖控制和预防CV并发症方面仍未得到充分管理。本研究的目的是调查克罗地亚全科医生(GPs)在开具抗糖尿病药物方面的实践和模式以及他们对指南的理解。:研究采用自行设计的匿名调查问卷,以数字形式发送至克罗地亚各地全科医生的电子邮箱地址。受访者仅为全科医生,对其特征没有任何限制。关于被诊断为T2D并开具特定药物的个体数量的数据基于受访者从其电子健康记录中的申报。:约59%的T2D患者仅由全科医生护理。在实现糖化血红蛋白(HbA1c)目标值方面,47%的T2D患者得到了良好管理。几乎所有受访者都声称他们至少每年审查一次规定的T2D治疗方案。共有47.6%的受访者阅读并完全理解了欧洲糖尿病研究协会(EASD)/美国糖尿病协会(ADA)指南,但58.3%的受访者在T2D治疗中应用了控制HbA1c水平和CV风险的双重原则。在伴有CV合并症的个体中,钠-葡萄糖协同转运蛋白2抑制剂(SGLT2ins)是最常开具的药物。:结果表明,克罗地亚全科医生仍倾向于应用过时的T2D治疗模式,但他们正在逐渐接受新的护理方案以及开具新型、更有效药物的建议。

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本文引用的文献

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BMC Prim Care. 2025 May 2;26(1):143. doi: 10.1186/s12875-025-02837-7.
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Referral reasons of type 2 diabetes patients from general practitioners to diabetes specialists: a cross-sectional observational study.2型糖尿病患者从全科医生转诊至糖尿病专科医生的转诊原因:一项横断面观察性研究。
BMC Prim Care. 2025 Apr 11;26(1):105. doi: 10.1186/s12875-025-02809-x.
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GLP-1RA and SGLT2i Medications for Type 2 Diabetes and Alzheimer Disease and Related Dementias.
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JAMA Neurol. 2025 May 1;82(5):439-449. doi: 10.1001/jamaneurol.2025.0353.
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Assessing Cardiovascular Target Attainment in Type 2 Diabetes Mellitus Patients in Tertiary Diabetes Center in Romania.评估罗马尼亚三级糖尿病中心2型糖尿病患者的心血管靶标达标情况。
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