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生物电阻抗分析与双能X线吸收法在儿科人群肥胖评估中的应用:一项系统评价

Bioelectrical Impedance Analysis Versus Dual X-Ray Absorptiometry for Obesity Assessment in Pediatric Populations: A Systematic Review.

作者信息

Manole Lorena Mihaela, Ghiga Gabriela, Iftinchi Otilia, Boca Laura Otilia, Donos Mădălina Andreea, Țarcă Elena, Ionuț Nistor, Revenco Ninel, Margasoiu Iulia, Trandafir Laura Mihaela

机构信息

Department of Mother and Child, Faculty of Medicine, Grigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.

Saint Mary Emergency Children Hospital, 700309 Iasi, Romania.

出版信息

Diagnostics (Basel). 2025 Jun 13;15(12):1505. doi: 10.3390/diagnostics15121505.

DOI:10.3390/diagnostics15121505
PMID:40564826
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12192207/
Abstract

: Pediatric obesity represents a significant public health challenge, requiring accurate and accessible tools for assessing body composition in pediatric populations. This systematic review (PROSPERO CRD42024592366) compares the methodological accuracy and clinical utility of bioelectrical impedance analysis (BIA) and dual x-ray absorptiometry (DXA) in evaluating obesity among children and adolescents. : Utilizing a comprehensive search across PubMed, EMBASE, and Web of Science between 1 January 2014 and 31 December 2024, we identified 28 studies meeting our inclusion criteria. The studies included involved participants aged 2-17 years with obesity and compared BIA with DXA as the reference standard. The exclusion criteria were studies focusing on adults, those that assessed BC solely using anthropometry, and those that did not report primary outcomes relevant to the comparison of BIA vs. DXA. : The findings reveal that despite recent technological advances improving BIA's precision, it consistently underestimates body fat percentage and fat mass, particularly in overweight and obese pediatric populations. DXA it is often used as a reference method in the evaluation of whole-body composition due to its higher accuracy and reliability. BIA offers significant practical advantages in accessibility, cost-effectiveness, and portability, but enhancements are needed to improve its accuracy for individual-level assessments. : While BIA shows promise as a practical tool for body composition assessment in children, its accuracy varies significantly by device type. Multi-frequency segmental analyzers, such as InBody 720, demonstrate better agreement with DXA, whereas simpler models tend to underestimate fat mass. Therefore, conclusions regarding BIA performance should be device-specific and its clinical utility should be carefully weighed based on the technology used.

摘要

小儿肥胖是一项重大的公共卫生挑战,需要准确且易于使用的工具来评估小儿群体的身体成分。本系统综述(PROSPERO CRD42024592366)比较了生物电阻抗分析(BIA)和双能X线吸收法(DXA)在评估儿童和青少年肥胖方面的方法学准确性和临床实用性。

利用2014年1月1日至2024年12月31日期间在PubMed、EMBASE和科学网进行的全面检索,我们确定了28项符合纳入标准的研究。这些研究纳入了年龄在2至17岁的肥胖参与者,并将BIA与作为参考标准的DXA进行了比较。排除标准为聚焦于成人的研究、仅使用人体测量学评估身体成分的研究以及未报告与BIA与DXA比较相关的主要结局的研究。

研究结果表明,尽管最近技术进步提高了BIA的精度,但它始终低估身体脂肪百分比和脂肪量,尤其是在超重和肥胖的小儿群体中。由于其更高的准确性和可靠性,DXA常用于评估全身成分的参考方法。BIA在可及性、成本效益和便携性方面具有显著的实际优势,但需要改进以提高其在个体水平评估中的准确性。

虽然BIA有望成为评估儿童身体成分的实用工具,但其准确性因设备类型而异。多频节段分析仪,如InBody 720,与DXA的一致性更好,而更简单的型号往往会低估脂肪量。因此,关于BIA性能的结论应因设备而异,其临床实用性应根据所使用的技术仔细权衡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c175/12192207/2acfd16a3bde/diagnostics-15-01505-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c175/12192207/2c4183e502e9/diagnostics-15-01505-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c175/12192207/2acfd16a3bde/diagnostics-15-01505-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c175/12192207/2c4183e502e9/diagnostics-15-01505-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c175/12192207/2acfd16a3bde/diagnostics-15-01505-g002.jpg

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本文引用的文献

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Compared to dual-energy X-ray absorptiometry, bioelectrical impedance effectively monitors longitudinal changes in body composition in children and adolescents with obesity during a lifestyle intervention.与双能X线吸收法相比,生物电阻抗能有效监测肥胖儿童和青少年在生活方式干预期间身体成分的纵向变化。
Nutr Res. 2025 Jan;133:1-12. doi: 10.1016/j.nutres.2024.11.003. Epub 2024 Nov 14.
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High-standard predictive equations for estimating body composition using bioelectrical impedance analysis: a systematic review.使用生物电阻抗分析预测身体成分的高精度预测方程:系统评价。
J Transl Med. 2024 May 29;22(1):515. doi: 10.1186/s12967-024-05272-x.
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Skeletal muscle mass, muscle strength, and physical performance in children and adolescents with obesity.
肥胖青少年的骨骼肌量、肌肉力量和身体机能。
Front Endocrinol (Lausanne). 2023 Oct 4;14:1252853. doi: 10.3389/fendo.2023.1252853. eCollection 2023.
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The bioelectrical impedance analysis (BIA) international database: aims, scope, and call for data.生物电阻抗分析(BIA)国际数据库:目标、范围和数据征集。
Eur J Clin Nutr. 2023 Dec;77(12):1143-1150. doi: 10.1038/s41430-023-01310-x. Epub 2023 Aug 2.
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Current Data and New Insights into the Genetic Factors of Atherogenic Dyslipidemia Associated with Metabolic Syndrome.与代谢综合征相关的致动脉粥样硬化性血脂异常遗传因素的当前数据及新见解
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