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纳米脂质体作为食品和健康领域抗氧化化合物的有效载体。

Nanoliposomes as Effective Vehicles of Antioxidant Compounds in Food and Health.

作者信息

García-Morales Jonathan, Fimbres-Olivarría Diana, González-Vega Ricardo Iván, Bernal-Mercado Ariadna Thalía, Aubourg-Martínez Santiago Pedro, López-Gastélum Karla Alejandra, Robles-García Miguel Ángel, de Jesús Ornelas-Paz José, Ruiz-Cruz Saúl, Del-Toro-Sánchez Carmen Lizette

机构信息

Departamento de Investigación y Posgrado en Alimentos, Universidad de Sonora, Blvd Luis Encinas & Rosales S/N, Hermosillo 83000, Sonora, Mexico.

Departamento de Investigaciones Científicas y Tecnológicas, Universidad de Sonora, Blvd Luis Donaldo Colosio S/N, Hermosillo 83000, Sonora, Mexico.

出版信息

Int J Mol Sci. 2025 Jun 9;26(12):5523. doi: 10.3390/ijms26125523.

Abstract

Nanoliposomes have increased exponentially since their discovery in the 1960s, primarily for encapsulating medicines or compounds that can improve human health. However, recent studies propose nanoliposomes as vehicles to protect, transport, and subsequently release compounds of various kinds to fortify the properties of foods and cause a prolonged release of encapsulated substances in a specific part of the body. Among the compounds successfully encapsulated are β-carotene; α-carotene; vitamins A, C, and D; and lycopene, among others. The encapsulation of extracts with high contents of antioxidant pigments is still to be explored. Therefore, this review aims to compile the compounds that have been successfully encapsulated and have met the specific prolonged release criteria, highlighting areas of research opportunity and application such as biomedical, pharmaceutical, and nutraceutical industries.

摘要

自20世纪60年代被发现以来,纳米脂质体呈指数级增长,主要用于封装可改善人类健康的药物或化合物。然而,最近的研究提出将纳米脂质体作为载体,用于保护、运输并随后释放各类化合物,以增强食品特性,并使封装物质在身体特定部位实现长效释放。成功封装的化合物包括β-胡萝卜素、α-胡萝卜素、维生素A、C和D以及番茄红素等。高含量抗氧化色素提取物的封装仍有待探索。因此,本综述旨在汇编已成功封装并符合特定长效释放标准的化合物,突出生物医学、制药和营养保健品行业等研究机会和应用领域。

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