• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

免疫之战中脂质的分子外交：连接罕见病与常见疾病的机制

Molecular Diplomacy of Lipids in the War of Immunity: Bridging Rare and Common Disease Mechanisms.

作者信息

Pandey Manoj Kumar

机构信息

Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA.

出版信息

Int J Mol Sci. 2025 Jun 10;26(12):5568. doi: 10.3390/ijms26125568.

DOI:10.3390/ijms26125568
PMID:40565032
Abstract

The panorama of biomedical and translational research is experiencing a profound conceptual evolution, one that calls for a reassessment of traditional binaries, such as active versus inactive, genetic versus epigenetic, and structural versus metabolic [...].

摘要

生物医学与转化研究的全景正在经历一场深刻的概念演变，这场演变要求重新审视传统的二元对立观念，例如主动与被动、基因与表观遗传、结构与代谢[……]。

相似文献

1
Molecular Diplomacy of Lipids in the War of Immunity: Bridging Rare and Common Disease Mechanisms.免疫之战中脂质的分子外交：连接罕见病与常见疾病的机制
Int J Mol Sci. 2025 Jun 10;26(12):5568. doi: 10.3390/ijms26125568.
2
Mapping current research status and emerging frontiers of lipidomics: a comprehensive data-mining-based study.脂质组学的当前研究现状与新兴前沿领域图谱绘制：一项基于全面数据挖掘的研究
Metabolomics. 2025 Jun 22;21(4):85. doi: 10.1007/s11306-025-02292-6.
3
Impact of residual disease as a prognostic factor for survival in women with advanced epithelial ovarian cancer after primary surgery.原发性手术后晚期上皮性卵巢癌患者残留病灶对生存预后的影响。
Cochrane Database Syst Rev. 2022 Sep 26;9(9):CD015048. doi: 10.1002/14651858.CD015048.pub2.
4
Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID-19.在基层医疗机构或医院门诊环境中，如果患者出现以下症状和体征，可判断其是否患有 COVID-19。
Cochrane Database Syst Rev. 2022 May 20;5(5):CD013665. doi: 10.1002/14651858.CD013665.pub3.
5
Pharmacological treatment for central sleep apnoea in adults.成人中枢性睡眠呼吸暂停的药物治疗。
Cochrane Database Syst Rev. 2023 Feb 27;2(2):CD012922. doi: 10.1002/14651858.CD012922.pub2.
6
Comparison of the effectiveness of inhaler devices in asthma and chronic obstructive airways disease: a systematic review of the literature.吸入装置在哮喘和慢性阻塞性气道疾病中的有效性比较：文献系统评价
Health Technol Assess. 2001;5(26):1-149. doi: 10.3310/hta5260.
7
Antidepressants for chronic non-cancer pain in children and adolescents.用于治疗儿童和青少年慢性非癌性疼痛的抗抑郁药。
Cochrane Database Syst Rev. 2017 Aug 5;8(8):CD012535. doi: 10.1002/14651858.CD012535.pub2.
8
The Effect of Endocrine Disorders on Lipids and Lipoproteins内分泌紊乱对脂质和脂蛋白的影响
9
Cuproptosis: a novel therapeutic mechanism in lung cancer.铜死亡：肺癌中的一种新型治疗机制。
Cancer Cell Int. 2025 Jun 24;25(1):231. doi: 10.1186/s12935-025-03864-1.
10
How to Implement Digital Clinical Consultations in UK Maternity Care: the ARM@DA Realist Review.如何在英国产科护理中实施数字临床会诊：ARM@DA实证主义综述
Health Soc Care Deliv Res. 2025 May 21:1-77. doi: 10.3310/WQFV7425.

本文引用的文献

1
5-Methylcytosine Methylation-Linked Hippo Pathway Molecular Interactions Regulate Lipid Metabolism.5-甲基胞嘧啶甲基化相关的 Hippo 信号通路分子相互作用调节脂质代谢。
Int J Mol Sci. 2025 Mar 12;26(6):2560. doi: 10.3390/ijms26062560.
2
Complement-mediated enhancement of SARS-CoV-2 antibody neutralisation potency in vaccinated individuals.补体介导的接种个体中SARS-CoV-2抗体中和效力增强
Nat Commun. 2025 Mar 18;16(1):2666. doi: 10.1038/s41467-025-57947-8.
3
Proteomics Profiling Reveals Pharmaceutical Excipient PEG400 Induces Nuclear-Receptor-Activation-Affected Lipid Metabolism and Metabolic Enzyme Expression.
蛋白质组学分析揭示药用辅料聚乙二醇400诱导核受体激活影响脂质代谢和代谢酶表达
Int J Mol Sci. 2025 Feb 18;26(4):1732. doi: 10.3390/ijms26041732.
4
Deciphering the Role of Cancer Stem Cells: Drivers of Tumor Evolution, Therapeutic Resistance, and Precision Medicine Strategies.解读癌症干细胞的作用：肿瘤进化、治疗抗性及精准医学策略的驱动因素
Cancers (Basel). 2025 Jan 24;17(3):382. doi: 10.3390/cancers17030382.
5
Granzyme K activates the entire complement cascade.颗粒酶K激活整个补体级联反应。
Nature. 2025 May;641(8061):211-221. doi: 10.1038/s41586-025-08713-9. Epub 2025 Feb 6.
6
Excipients in drug delivery systems: A comprehensive review of approved inactive ingredients for human ophthalmic formulations.药物递送系统中的辅料：人眼用制剂已批准的非活性成分综述
Eur J Pharm Biopharm. 2025 Mar;208:114637. doi: 10.1016/j.ejpb.2025.114637. Epub 2025 Jan 19.
7
Complement System and Adhesion Molecule Skirmishes in Fabry Disease: Insights into Pathogenesis and Disease Mechanisms.补体系统与黏附分子在法布瑞氏病中的交锋：对发病机制和疾病机制的深入了解。
Int J Mol Sci. 2024 Nov 14;25(22):12252. doi: 10.3390/ijms252212252.
8
Epigenetics-targeted drugs: current paradigms and future challenges.表观遗传学靶向药物：当前范例与未来挑战。
Signal Transduct Target Ther. 2024 Nov 26;9(1):332. doi: 10.1038/s41392-024-02039-0.
9
Targeting Lipid Metabolism in Cancer Stem Cells for Anticancer Treatment.靶向肿瘤干细胞的脂代谢用于癌症治疗。
Int J Mol Sci. 2024 Oct 17;25(20):11185. doi: 10.3390/ijms252011185.
10
Complement activation and lung injury in Japanese patients with COVID-19: a prospective observational study.COVID-19 患者补体激活与肺损伤：一项前瞻性观察研究。
Sci Rep. 2024 Oct 22;14(1):24895. doi: 10.1038/s41598-024-76365-2.