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1990年至2021年10至19岁青少年下背痛的全球、区域和国家负担:全球疾病负担研究2021的系统分析

Global, Regional and National Burden of Low Back Pain in Adolescents Aged 10-19 years, 1990-2021: A Systematic Analysis of the Global Burden of Disease Study 2021.

作者信息

Wang Shuang, Zhang Shouyao, Li Min, Chen Suyu, Chen Yiping, Song Yongli, Zhang Xinghe

机构信息

Second Clinical Medical College/Second Affiliated Hospital, Yunnan University of Chinese Medicine, Kunming, 650000, People's Republic of China.

School of Basic Medicine, Yunnan University of Chinese Medicine, Kunming, 650000, People's Republic of China.

出版信息

J Pain Res. 2025 Jun 26;18:3171-3183. doi: 10.2147/JPR.S525330. eCollection 2025.

DOI:10.2147/JPR.S525330
PMID:40599254
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12209532/
Abstract

OBJECTIVE

To comprehensively analyze the levels and trends of low back pain (LBP) prevalence, incidence, and years lived with disability (YLDs) among adolescents aged 10-19 globally from 1990 to 2021, stratified by sex and the Socio - Demographic Index (SDI), and analyze the risk factors.

SUMMARY OF BACKGROUND DATA

LBP affects adolescents, but its global burden and trends among this age group need exploration.

METHODS

Estimations were carried out using the Bayesian meta-regression tool, DisMod-MR(Disease Modeling Meta-Regression) 2.1. The estimated annual percentage change (EAPC) was calculated based on the linear regression patterns of age-standardized rates and calendar years to represent the temporal trends of age-standardized rates. Data analysis and visualization were performed using the R software (version 4.2.2).

RESULTS

In 2021, global 10-19 years old had 38,476,826 (95% UI, 29,229,615-49,665,830) incident LBP cases, 19,234,452 (95% UI, 14,487,990-24,798,451) prevalent cases, and 4,205,995 (95% UI, 2,713,716-5,947,074) total YLDs. ASPR (Age-Standardized Prevalence Rate), ASIR (Age-Standardized Incidence Rate), ASYR (Age-Standardized YLDs Rate) declined. Females had higher rates. ASYR and SDI were positively correlated. Hungary, Czech Republic, Romania had high national prevalence; certain regions had big increases. Occupational risks were the only risk factor.

CONCLUSION

LBP still causes high distress to adolescents aged 10-19 and seriously affects their physical and mental health. The burden of LBP remains high. It is necessary to increase the public and policymakers' awareness of its risk factors and take preventive measures to reduce the future burden of this disease.

摘要

目的

全面分析1990年至2021年全球10至19岁青少年中腰痛(LBP)的患病率、发病率和残疾生存年数(YLDs)的水平及趋势,按性别和社会人口指数(SDI)分层,并分析风险因素。

背景数据总结

腰痛影响青少年,但其在该年龄组中的全球负担和趋势尚需探索。

方法

使用贝叶斯元回归工具DisMod-MR(疾病建模元回归)2.1进行估计。基于年龄标准化率和历年的线性回归模式计算估计年百分比变化(EAPC),以代表年龄标准化率的时间趋势。使用R软件(版本4.2.2)进行数据分析和可视化。

结果

2021年,全球10至19岁青少年有38476826例(95%不确定区间,29229615 - 49665830)新发腰痛病例,19234452例(95%不确定区间,14487990 - 24798451)现患病例,以及4205995例(95%不确定区间,2713716 - 5947074)总残疾生存年数。年龄标准化患病率(ASPR)、年龄标准化发病率(ASIR)、年龄标准化残疾生存年数率(ASYR)下降。女性患病率更高。ASYR与SDI呈正相关。匈牙利、捷克共和国、罗马尼亚国家患病率较高;某些地区有大幅上升。职业风险是唯一的风险因素。

结论

腰痛仍给10至19岁青少年带来高度痛苦,严重影响他们的身心健康。腰痛负担仍然很高。有必要提高公众和政策制定者对其风险因素的认识,并采取预防措施以减轻该疾病未来的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5354/12209532/0b0c8434a764/JPR-18-3171-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5354/12209532/fb971a7e77c9/JPR-18-3171-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5354/12209532/c1b5671433a6/JPR-18-3171-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5354/12209532/bd0fe516e59b/JPR-18-3171-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5354/12209532/0b0c8434a764/JPR-18-3171-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5354/12209532/fb971a7e77c9/JPR-18-3171-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5354/12209532/c1b5671433a6/JPR-18-3171-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5354/12209532/bd0fe516e59b/JPR-18-3171-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5354/12209532/0b0c8434a764/JPR-18-3171-g0005.jpg

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