Oftalvist CIO Jerez , Jerez de la Frontera, Spain.
Oftalvist , Alicante, Spain.
Expert Rev Med Devices. 2020 Jun;17(6):591-597. doi: 10.1080/17434440.2020.1772050. Epub 2020 Jun 11.
To assess the repeatability of ocular biometric parameters using a high-resolution imaging device.
74 healthy right eyes were included in this study. Five-repeated measurements were taken with ANTERION high-resolution swept-source optical coherence tomographer (SS-OCT) to measure: corneal thickness (central and at 2, 4 and 6-mm diameters), aqueous depth (AD), lens thickness (LT), anterior chamber volume (ACV), axial length (AL), and pupil (diameter and position). The intrasubject standard deviation (S), coefficient of repeatability (CoR) and intraclass correlation coefficient (ICC) were calculated. Bland-Altman method was applied to analyze the difference between the first and the last measurement. The average and the difference between both measurements were calculated for all parameters.
We have not found statistically significant differences between repeated measurements (p > 0.05). The mean difference for corneal thickness was between -0.08 and 0.28 μm. For AD and LT was 0.004 and -0.004 μm, respectively. ACV mean difference was -0.03 mm and for AL was 0.001 mm. Pupil diameter and position mean differences ranged between -0.008 and 0.009 mm. Overall, most ocular parameters had a S <1 and a CoR <2 in their respective units, and an ICC >0.92.
The ANTERION high-resolution SS-OCT device provides good repeatability for different ocular biometric measurements.
使用高分辨率成像设备评估眼部生物测量参数的可重复性。
本研究纳入了 74 只健康的右眼。使用 ANTERION 高分辨率扫频源光学相干断层扫描仪（SS-OCT）进行 5 次重复测量，以测量：角膜厚度（中央和 2、4 和 6mm 直径处）、房水深度（AD）、晶状体厚度（LT）、前房容积（ACV）、眼轴长度（AL）和瞳孔（直径和位置）。计算了组内标准差（S）、可重复性系数（CoR）和组内相关系数（ICC）。采用 Bland-Altman 法分析了第一次和最后一次测量之间的差异。计算了所有参数的平均值和两次测量之间的差值。
我们没有发现重复测量之间存在统计学上的显著差异（p>0.05）。角膜厚度的平均差值在-0.08 至 0.28μm 之间。AD 和 LT 的差值分别为 0.004μm 和-0.004μm。ACV 的平均差值为-0.03mm，AL 的平均差值为 0.001mm。瞳孔直径和位置的平均差值在-0.008 至 0.009mm 之间。总体而言，大多数眼部参数的 S<1，CoR<2，ICC>0.92。
ANTERION 高分辨率 SS-OCT 设备可提供不同眼部生物测量的良好重复性。
