T Ranjith Kumar, G Lakshmi Priya
School of Electronics Engineering, Vellore Institute of Technology, Chennai, 600127, India.
Centre for Advanced Materials and Innovative Technologies, Vellore Institute of Technology, Chennai, 600127, India.
Sci Rep. 2025 Jul 5;15(1):24026. doi: 10.1038/s41598-025-08892-5.
This work presents a comprehensive investigation of symmetric (HJ-DD-UTFET) and asymmetric Source Drain Heterojunction Dual Dielectric Uniform Tunnel Field-Effect Transistors (A-SD-HJ-DD-UTFET) to achieve enhanced analog/RF, and linearity performance. The A-SD-HJ-DD-UTFET showcases an extremely low OFF current level of 8.124 × 10 A/μm which surpasses the symmetric HJ-DD-UTFET by 5,470 times and presents a high ON-OFF ratio of 2.83 × 10 representing a 6,261 times improvement. This enhanced performance occurs because of structural asymmetry which makes it suitable for high-end RF and biosensing purposes while reaching a peak transconductance of 536 µS. For dengue NS1 protein detection (κ = 78.7), the TCAD-driven model of the proposed A-SD-HJ-DD-UTFET biosensor delivers a distinctive label-free detection method, achieving a peak transconductance (g) of 577 µS, cut-off frequency (f) of 193 GHz, Gain-Bandwidth Product (GBP) of 201 GHz, Transconductance Generation factor (TGF) of 155 V, and gain transconductance frequency product (GTFP) of 25.9 THz. These correspond to improvements of 51.4%, 13.5%, 26.4%, 96.4%, and 45.5%, respectively, over SARS-CoV spike protein detection (κ = 2). The A-SD-HJ-DD-UTFET biosensor also exhibits superior linearity performance during dengue NS1 protein detection through its desirable intercept points, minimal intermodulation distortion, and a well-maintained 1 dB compression point, affirming its potential as a high-speed, label-free RF biosensor for infectious disease Point of Care Testing (POCT) diagnostics.
这项工作对对称（HJ-DD-UTFET）和非对称源漏异质结双介质均匀隧道场效应晶体管（A-SD-HJ-DD-UTFET）进行了全面研究，以实现增强的模拟/射频和线性性能。A-SD-HJ-DD-UTFET展现出极低的关态电流水平，为8.124×10 A/μm，比对称HJ-DD-UTFET高出5470倍，且具有2.83×10的高开/关比，提高了6261倍。这种性能的提升源于结构不对称性，使其适用于高端射频和生物传感用途，同时达到了536 μS的峰值跨导。对于登革热NS1蛋白检测（κ = 78.7），所提出的A-SD-HJ-DD-UTFET生物传感器的TCAD驱动模型提供了一种独特的无标记检测方法，实现了577 μS的峰值跨导（g）、193 GHz的截止频率（f）、201 GHz的增益带宽积（GBP）、155 V的跨导产生因子（TGF）以及25.9 THz的增益跨导频率积（GTFP）。与严重急性呼吸综合征冠状病毒刺突蛋白检测（κ = 2）相比，这些指标分别提高了51.4%、13.5%、26.4%、96.4%和45.5%。A-SD-HJ-DD-UTFET生物传感器在登革热NS1蛋白检测过程中还通过其理想的截点、最小的互调失真和良好维持的1 dB压缩点展现出卓越的线性性能，证实了其作为用于传染病即时检测（POCT）诊断的高速、无标记射频生物传感器的潜力。
