• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

小关节阻滞与内侧支阻滞在脊柱疼痛管理中的有效性：一项系统评价和荟萃分析

Effectiveness of a Facet Joint Block Versus a Medial Branch Block in Spinal Pain Management: A Systematic Review and Meta-Analysis.

作者信息

Noh Sung Hyeon, Kim Kyoung-Tae, Shin Dong Ah, Yun Je Hwi, Cho Pyung Goo, Kim Sang Hyun

机构信息

Department of Neurosurgery, Ajou University School of Medicine, Suwon, Korea.

Department of Neurosurgery, Bokwang Hospital, Daegu, Korea.

出版信息

Neurospine. 2025 Jun;22(2):441-450. doi: 10.14245/ns.2550384.192. Epub 2025 Jun 30.

DOI:10.14245/ns.2550384.192
PMID:40625008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12242727/
Abstract

OBJECTIVE

Facet joint injections (FJIs) and medial branch blocks (MBBs) are commonly used interventions for chronic spinal pain, but their comparative effectiveness remains unclear. This meta-analysis aimed to compare the pain relief, functional improvement, complications, and patient satisfaction associated with FJI and MBB.

METHODS

A systematic review and meta-analysis of randomized controlled trials and observational studies were conducted. Primary outcomes included pain relief (numerical rating scale) and functional improvement (Oswestry Disability Index [ODI]/Neck Disability Index). Secondary outcomes assessed adverse effects and patient satisfaction. The differences in characteristics between patients who were readmitted and those who were not were identified and analyzed using the Review Manager software.

RESULTS

FJI resulted in lower pain and ODI scores compared to MBB, but the differences were not statistically significant. However, patient satisfaction was significantly higher in the FJI group (odds ratio, 1.81; 95% confidence interval, 1.02-3.24; p=0.04). Additionally, FJI had fewer adverse effects than MBB.

CONCLUSION

Both FJI and MBB are effective for chronic spinal pain, but FJI may be preferred for patients seeking immediate pain relief with fewer complications. Further high-quality studies are needed to refine treatment guidelines.

摘要

目的

小关节突关节注射（FJIs）和内侧支阻滞（MBBs）是慢性脊柱疼痛常用的干预措施，但其相对有效性仍不明确。本荟萃分析旨在比较FJIs和MBBs在疼痛缓解、功能改善、并发症及患者满意度方面的差异。

方法

对随机对照试验和观察性研究进行系统评价和荟萃分析。主要结局指标包括疼痛缓解（数字评分量表）和功能改善（奥斯威斯利功能障碍指数[ODI]/颈部功能障碍指数）。次要结局指标评估不良反应和患者满意度。使用Review Manager软件识别并分析再次入院患者与未再次入院患者在特征上的差异。

结果

与MBBs相比，FJIs导致更低的疼痛和ODI评分，但差异无统计学意义。然而，FJIs组患者满意度显著更高（优势比，1.81；95%置信区间，1.02 - 3.24；p = 0.04）。此外，FJIs的不良反应比MBBs少。

结论

FJIs和MBBs对慢性脊柱疼痛均有效，但对于寻求立即缓解疼痛且并发症较少的患者，FJIs可能更受青睐。需要进一步开展高质量研究以完善治疗指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/95578e057d51/ns-2550384-192f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/8b5cb80d6454/ns-2550384-192f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/88d3a7855afa/ns-2550384-192f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/f6b4ccb5321c/ns-2550384-192f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/f60f9b16dc09/ns-2550384-192f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/1a7069585bcb/ns-2550384-192f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/0599dba6355f/ns-2550384-192f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/b6b34a675be6/ns-2550384-192f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/95578e057d51/ns-2550384-192f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/8b5cb80d6454/ns-2550384-192f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/88d3a7855afa/ns-2550384-192f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/f6b4ccb5321c/ns-2550384-192f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/f60f9b16dc09/ns-2550384-192f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/1a7069585bcb/ns-2550384-192f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/0599dba6355f/ns-2550384-192f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/b6b34a675be6/ns-2550384-192f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec4e/12242727/95578e057d51/ns-2550384-192f8.jpg

相似文献

1
Effectiveness of a Facet Joint Block Versus a Medial Branch Block in Spinal Pain Management: A Systematic Review and Meta-Analysis.小关节阻滞与内侧支阻滞在脊柱疼痛管理中的有效性：一项系统评价和荟萃分析
Neurospine. 2025 Jun;22(2):441-450. doi: 10.14245/ns.2550384.192. Epub 2025 Jun 30.
2
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.系统性药理学治疗慢性斑块状银屑病：网络荟萃分析。
Cochrane Database Syst Rev. 2021 Apr 19;4(4):CD011535. doi: 10.1002/14651858.CD011535.pub4.
3
Antidepressants for pain management in adults with chronic pain: a network meta-analysis.抗抑郁药治疗成人慢性疼痛的疼痛管理：一项网络荟萃分析。
Health Technol Assess. 2024 Oct;28(62):1-155. doi: 10.3310/MKRT2948.
4
Epidural versus non-epidural or no analgesia for pain management in labour.硬膜外镇痛与非硬膜外镇痛或无镇痛用于分娩疼痛管理的比较。
Cochrane Database Syst Rev. 2018 May 21;5(5):CD000331. doi: 10.1002/14651858.CD000331.pub4.
5
Intravenous magnesium sulphate and sotalol for prevention of atrial fibrillation after coronary artery bypass surgery: a systematic review and economic evaluation.静脉注射硫酸镁和索他洛尔预防冠状动脉搭桥术后房颤：系统评价与经济学评估
Health Technol Assess. 2008 Jun;12(28):iii-iv, ix-95. doi: 10.3310/hta12280.
6
A systematic review of therapeutic facet joint interventions in chronic spinal pain.慢性脊柱疼痛中治疗性小关节干预的系统评价
Pain Physician. 2007 Jan;10(1):229-53.
7
Hypnosis for pain management during labour and childbirth.分娩过程中疼痛管理的催眠疗法。
Cochrane Database Syst Rev. 2016 May 19;2016(5):CD009356. doi: 10.1002/14651858.CD009356.pub3.
8
Manipulation and mobilisation for neck pain contrasted against an inactive control or another active treatment.针对颈部疼痛的手法治疗和松动术与非主动对照或另一种主动治疗的对比。
Cochrane Database Syst Rev. 2015 Sep 23;2015(9):CD004249. doi: 10.1002/14651858.CD004249.pub4.
9
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of topotecan for ovarian cancer.拓扑替康治疗卵巢癌的临床有效性和成本效益的快速系统评价。
Health Technol Assess. 2001;5(28):1-110. doi: 10.3310/hta5280.
10
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.慢性斑块状银屑病的全身药理学治疗：一项网状Meta分析。
Cochrane Database Syst Rev. 2020 Jan 9;1(1):CD011535. doi: 10.1002/14651858.CD011535.pub3.

本文引用的文献

1
Comparative Evaluation of Intraarticular Facet Joint Injection Versus Medial Branch Block in Patients With Low Back Pain: A Randomised Controlled Study.腰痛患者关节内小关节突关节注射与内侧支阻滞的比较评估：一项随机对照研究。
Cureus. 2023 Nov 22;15(11):e49232. doi: 10.7759/cureus.49232. eCollection 2023 Nov.
2
Comparative Efficacy of Clinical Interventions for Sacroiliac Joint Pain: Systematic Review and Network Meta-analysis With Preliminary Design of Treatment Algorithm.骶髂关节疼痛临床干预措施的比较疗效：系统评价与网状Meta分析及治疗算法的初步设计
Neurospine. 2023 Sep;20(3):997-1010. doi: 10.14245/ns.2346586.293. Epub 2023 Sep 30.
3
Relationships Between Skeletal Muscle Mass, Lumbar Lordosis, and Chronic Low Back Pain in the Elderly.
老年人骨骼肌质量、腰椎前凸与慢性下腰痛之间的关系
Neurospine. 2023 Sep;20(3):959-968. doi: 10.14245/ns.2346494.247. Epub 2023 Sep 30.
4
A pragmatic randomized prospective trial of cooled radiofrequency ablation of the medial branch nerves versus facet joint injection of corticosteroid for the treatment of lumbar facet syndrome: 12 month outcomes.一项关于冷却射频消融治疗腰椎小关节综合征的中支神经与关节内注射皮质类固醇的实用随机前瞻性试验：12 个月的结果。
Pain Med. 2023 Dec 1;24(12):1318-1331. doi: 10.1093/pm/pnad107.
5
Cochrane's risk of bias tool for non-randomized studies (ROBINS-I) is frequently misapplied: A methodological systematic review.Cochrane 的非随机研究偏倚风险工具（ROBINS-I）经常被错误应用：一项方法学系统评价。
J Clin Epidemiol. 2021 Dec;140:22-32. doi: 10.1016/j.jclinepi.2021.08.022. Epub 2021 Aug 23.
6
The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.PRISMA 2020 声明：系统评价报告的更新指南。
BMJ. 2021 Mar 29;372:n71. doi: 10.1136/bmj.n71.
7
Comparing the Efficacy of Combined Treatment with Medial Branch Block and Facet Joint Injection in Axial Low Back Pain.比较联合治疗与经皮椎间孔镜下射频消融术治疗腰椎间盘突出症的疗效。
Pain Res Manag. 2021 Jan 7;2021:1343891. doi: 10.1155/2021/1343891. eCollection 2021.
8
Effectiveness of Lumbar Facet Joint Blocks and Predictive Value before Radiofrequency Denervation: The Facet Treatment Study (FACTS), a Randomized, Controlled Clinical Trial.腰椎小关节阻滞的疗效及射频消融术前的预测价值：关节治疗研究（FACTS），一项随机对照临床试验。
Anesthesiology. 2018 Sep;129(3):517-535. doi: 10.1097/ALN.0000000000002274.
9
Comparison of Intra-articular Thoracic Facet Joint Steroid Injection and Thoracic Medial Branch Block for the Management of Thoracic Facet Joint Pain.关节内胸椎关节突关节类固醇注射与胸椎内侧支阻滞治疗胸椎关节突关节痛的比较。
Spine (Phila Pa 1976). 2018 Jan 15;43(2):76-80. doi: 10.1097/BRS.0000000000002269.
10
ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions.ROBINS-I：一种评估干预性非随机研究偏倚风险的工具。
BMJ. 2016 Oct 12;355:i4919. doi: 10.1136/bmj.i4919.