Liu Ruoshuang, Wu Menghuan, Cheng Xia, Zhou Chundi, Cheng Caiqin, Feng Lijun, Shen Yirong
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Department of Endocrinology, Shanghai Putuo District Liqun Hospital, Shanghai, China.
Discov Oncol. 2025 Jul 17;16(1):1358. doi: 10.1007/s12672-025-03185-9.
Sarcopenia is common among patients with cancer. The alterations in the internal milieu of cancer patients, coupled with the adverse effects of antineoplastic therapies, markedly augment the susceptibility to sarcopenia. We aimed to clarify the current research status and investigate future trends in sarcopenia and cancer research.
Publications on sarcopenia and cancer from the past decade were retrieved from the Web of Science database. VOSviewer, CiteSpace, and Bibliometrix R package were used for visualization analysis.
A total of 3749 publications were retrieved between 2014 and 2023. These publications were written by 21,507 authors affiliated with 4068 organizations in 76 countries/regions. Japan, the United States, and China constituted the primary contributors to the majority of the publications. The top three research institutions with the highest outputs in this field were the University of Alberta, Wenzhou Medical University, and Maastricht University. The Journal of Cachexia Sarcopenia and Muscle served as the pivotal and most cited journal in this field. Baracos VE from the University of Alberta was the author with the most publications. "Sarcopenic obesity", "Radiomics", and "Neutrophil/lymphocyte ratio" were highly focused topics in current research.
This study conducted the first bibliometric analysis of literature on sarcopenia and cancer. A systematic analysis of the present research status and emerging trends in this field provides important references for future research.
肌肉减少症在癌症患者中很常见。癌症患者体内环境的改变，再加上抗肿瘤治疗的不良反应，显著增加了患肌肉减少症的易感性。我们旨在阐明肌肉减少症与癌症研究的当前现状，并探究未来趋势。
从科学网数据库中检索过去十年关于肌肉减少症与癌症的出版物。使用VOSviewer、CiteSpace和Bibliometrix R包进行可视化分析。
2014年至2023年间共检索到3749篇出版物。这些出版物由来自76个国家/地区4068个组织的21507名作者撰写。日本、美国和中国是大多数出版物的主要贡献者。该领域产出最高的前三所研究机构是阿尔伯塔大学、温州医科大学和马斯特里赫特大学。《恶病质、肌肉减少症与肌肉杂志》是该领域的关键且被引用最多的期刊。阿尔伯塔大学的Baracos VE是发表文章最多的作者。“肌肉减少性肥胖”“放射组学”和“中性粒细胞/淋巴细胞比值”是当前研究中高度关注的主题。
本研究首次对肌肉减少症与癌症的文献进行了文献计量分析。对该领域当前研究现状和新趋势的系统分析为未来研究提供了重要参考。
