使用DNA亲和纯化测序（DAP-seq）来鉴定潜在的DSM12444转录因子的结合位点。
Using DNA affinity purification sequencing (DAP-seq) to identify binding sites of potential DSM12444 transcription factors.
作者信息
Myers Kevin S, Linz Alexandra M, Baumgart Leo A, Zhang Yu, Blaby Ian, Mewalal Ritesh, Ng Vivian, Noguera Daniel R, Donohue Timothy J
机构信息
Wisconsin Energy Institute and Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, Wisconsin, USA.
U.S. Department of Energy, Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
出版信息
Microbiol Resour Announc. 2025 Aug 14;14(8):e0026025. doi: 10.1128/mra.00260-25. Epub 2025 Jul 22.
Abstract
Genome-wide binding sites of 44 putative transcription factors (TFs) from DSM12444 were analyzed using DNA affinity purification sequencing. We report that 32 of these TFs have at least one area of enrichment. These data will help better understand aromatic metabolism and other features of biology.
摘要
利用DNA亲和纯化测序技术分析了来自DSM12444的44个假定转录因子（TFs）的全基因组结合位点。我们报告称，这些转录因子中有32个至少有一个富集区域。这些数据将有助于更好地理解芳香族代谢及生物学的其他特征。
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