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2009年至2021年巴西里约热内卢州孕产妇和晚期死亡率趋势,重点关注甲型H1N1流感和新型冠状病毒肺炎疫情。

Maternal and late mortality trends, emphasizing the H1N1 and COVID-19 pandemics, in the state of Rio de Janeiro, Brazil, from 2009 to 2021.

作者信息

Bellizzi Ana Lucia de Melo, Cascão Angela Maria, Brito Alexandre Dos Santos, Fonseca Sandra Costa, Kale Pauline Lorena

机构信息

Universidade Federal do Rio de Janeiro, Institute for Collective Health Studies, Graduate Program - Rio de Janeiro (RJ), Brazil.

Secretaria Estadual de Saúde do Rio de Janeiro, Undersecretariat for Health Surveillance - Rio de Janeiro (RJ), Brazil.

出版信息

Rev Bras Epidemiol. 2025 Jul 21;28:e250037. doi: 10.1590/1980-549720250037. eCollection 2025.

Abstract

OBJECTIVE

Trends in maternal mortality (MMR) and late maternal mortality ratios (LMMR) were estimated, in periods with and without H1N1 and COVID-19 pandemics, in Rio de Janeiro, Brazil, from 2009 to 2021.

METHODS

Ecological study of temporal trends. Data was obtained from the Mortality and Live Birth Information Systems. The annual MMR and LMMR per 100,000 live births (LB) were calculated and the trends were estimated using the joinpoint regression model.

RESULTS

In 2009, the MMR was 103.1, reaching 152.4/100,000 LB in 2021, with an annual reduction of 3.3% (95% confidence interval - 95%CI -5.5; -1.7) until 2019 and an increase of 51.2% (95%CI 23.5; 64.5) in 2020/21. Excluding the years of the COVID-19 pandemic, it was observed that an annual decline of 3.3% and, with the concomitant exclusion of the years of the H1N1 pandemic, stability. The LMMR were 8.3 (2009) and 22.2 (2021) per 100,000 LB, with an annual growth of 28.2% (95%CI 11.8; 47.8) until 2011, remaining stationary from 2011 to 2015, followed by an increase of 11.7% until 2021; with the exclusion of the final biennium, the trend is upward (3.8%) and also with the exclusion of the initial biennium, the trend became downward (7%) until 2014 and upward (8.2%) from then on.

CONCLUSION

There was a change in trend with the separate or joint incorporation of pandemic biennia: without pandemics, maternal mortality would be stationary, despite actions to prevent maternal deaths, and late maternal mortality, would be descending until 2014 and then ascending, crediting itself in part, to improving death investigation.

摘要

目的

估算2009年至2021年期间,在巴西里约热内卢,有甲型H1N1流感和新冠疫情以及无疫情期间的孕产妇死亡率(MMR)和晚期孕产妇死亡率(LMMR)趋势。

方法

对时间趋势进行生态学研究。数据来自死亡和活产信息系统。计算每10万例活产的年度MMR和LMMR,并使用连接点回归模型估算趋势。

结果

2009年,MMR为103.1,2021年达到152.4/10万例活产,到2019年每年下降3.3%(95%置信区间-5.5;-1.7),2020/21年增加51.2%(95%置信区间23.5;64.5)。排除新冠疫情年份后,观察到每年下降3.3%,同时排除甲型H1N1流感疫情年份后,趋势稳定。LMMR分别为2009年的8.3和2021年的22.2/10万例活产,到2011年每年增长28.2%(95%置信区间11.8;47.8),2011年至2015年保持平稳,随后到2021年增加11.7%;排除最后两年,趋势上升(3.8%),同时排除最初两年,趋势到2014年下降(7%),此后上升(8.2%)。

结论

疫情两年单独或共同纳入时趋势发生变化:无疫情时,尽管采取了预防孕产妇死亡的行动,但孕产妇死亡率将保持平稳,晚期孕产妇死亡率到2014年将下降然后上升,部分原因是死亡调查有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7695/12278847/bd03d0d5e35b/1980-5497-rbepid-28-e250037-gf1.jpg

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