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前臂骨折的发病率、患病率及伤残调整生命年:基于2021年全球疾病负担研究的系统分析

The incidence, prevalence, and years lived with disability of forearm fractures: a systematic analysis based on the global burden of disease study 2021.

作者信息

Fan Xiaobo, Yang Zongyou, Liu Yuan, Wei Zhikun, Zhao Chenyang, Pang Chaojian

机构信息

Department of Orthopaedic Surgery, The First Hospital of Handan, Handan, China.

Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China.

出版信息

Front Public Health. 2025 Jul 10;13:1598660. doi: 10.3389/fpubh.2025.1598660. eCollection 2025.

Abstract

PURPOSE

Forearm fractures significantly impact global health and socioeconomic systems. This study examines forearm fracture burden across 204 countries and territories from 1990 to 2021.

METHODS

Data from Global Burden of Disease (GBD) 2021 were analyzed, including incidence (new cases occurring each year), prevalence (total existing cases at a given time), years lived with disability (YLDs, measuring time lived with reduced health due to injury), and causes categorized by injury mechanisms. Age-standardized rates (ASRs) with 95% uncertainty intervals (UIs) were calculated to address demographic variability. Trends were stratified by region, age, sex, and injury etiology.

RESULTS

Globally, forearm fracture cases increased by 22.25% (from 26.1 to 31.9 million), while age-standardized incidence rates declined by 16.75% (to 402.35 per 100,000). Prevalence rose by 39.12% (from 4.5 to 6.2 million cases), with YLDs increasing by 42.22% (from 144,166 to 205,031). Regional variations were substantial: Oceania experienced the highest incidence surge (150%), whereas Central Europe saw a 32.17% decline. Sex-specific analysis revealed marked disparities: in the ≥75 age groups, female prevalence rates were approximately double those of males (>800 per 100,000 vs. ~300 per 100,000 for ages 95+). Among the older adult (≥60 years), females showed a steeper increase in YLD rates, reaching 30 per 100,000 in the 95 + age group compared with 15 per 100,000 in males. Falls were the predominant cause, particularly in Central/Eastern Europe (>500 per 100,000).

CONCLUSION

Despite declining age-standardized rates, the absolute cases of forearm fractures is rising due to population aging and uneven healthcare access. Sex-specific prevention strategies are needed, emphasizing osteoporosis screening for postmenopausal women and workplace safety measures in regions with high mechanical-force injuries. Policymakers should prioritize resources for high-burden regions and implement targeted fall prevention programs.

摘要

目的

前臂骨折对全球健康和社会经济系统产生重大影响。本研究调查了1990年至2021年期间204个国家和地区的前臂骨折负担情况。

方法

分析了全球疾病负担(GBD)2021的数据,包括发病率(每年新发病例数)、患病率(特定时间的现存病例总数)、伤残调整生命年(YLDs,衡量因伤导致健康状况下降的生存时间)以及按损伤机制分类的病因。计算了具有95%不确定性区间(UIs)的年龄标准化率(ASRs),以应对人口结构差异。趋势按地区、年龄、性别和损伤病因进行分层。

结果

全球范围内,前臂骨折病例增加了22.25%(从2610万例增至3190万例),而年龄标准化发病率下降了16.75%(降至每10万人402.35例)。患病率上升了39.12%(从450万例增至620万例),YLDs增加了42.22%(从144166例增至205031例)。地区差异显著:大洋洲发病率激增最高(150%),而中欧下降了32.17%。按性别分析显示出明显差异:在75岁及以上年龄组中,女性患病率约为男性的两倍(95岁及以上年龄组中,女性每10万人超过800例,男性约为每10万人300例)。在老年人(≥60岁)中,女性的YLD率上升更为陡峭,在95岁及以上年龄组中达到每10万人30例,而男性为每10万人15例。跌倒为主要原因,尤其是在中东欧地区(每10万人超过500例)。

结论

尽管年龄标准化率有所下降,但由于人口老龄化和医疗服务获取不均衡,前臂骨折的绝对病例数仍在上升。需要针对性别的预防策略,强调对绝经后女性进行骨质疏松症筛查,以及在机械力损伤高发地区采取工作场所安全措施。政策制定者应优先为高负担地区分配资源,并实施有针对性的跌倒预防计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b6b/12287112/235e73345d13/fpubh-13-1598660-g001.jpg

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