Morris J G, Tenney J H, Drusano G L
Antimicrob Agents Chemother. 1985 Sep;28(3):442-5. doi: 10.1128/AAC.28.3.442.
The in vitro activity of norfloxacin and six other antimicrobial agents was tested against 93 vibrio strains representing the currently described pathogenic Vibrio species. Norfloxacin had excellent activity against all species, with the following MICs for 90% of the strains: 0.016 micrograms/ml for Vibrio cholerae (including tetracycline-resistant V. cholerae O1 strains), 0.25 micrograms/ml for V. parahaemolyticus, and 0.063 micrograms/ml for V. vulnificus.
对诺氟沙星及其他六种抗菌剂的体外活性进行了测试，受试对象为93株代表当前已描述的致病性弧菌物种的弧菌菌株。诺氟沙星对所有物种均具有优异活性，对于90%的菌株，其最低抑菌浓度（MIC）如下：霍乱弧菌为0.016微克/毫升（包括四环素耐药的霍乱弧菌O1菌株），副溶血性弧菌为0.25微克/毫升，创伤弧菌为0.063微克/毫升。
