伊朗南部霍尔木兹甘省康复中心智障患者肠道微孢子虫的患病率
Prevalence of Intestinal Microsporidia in Patients with Intellectual Disabilities in Rehabilitation Centers of Hormozgan Province, Southern Iran.
作者信息
Kamrani Fatima, Omidian Mostafa, Turki Habibollah, Agholi Mahmoud, Sarkari Bahador
机构信息
Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Infectious and Tropical Diseases Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
出版信息
Iran J Parasitol. 2025 Apr-Jun;20(2):236-244. doi: 10.18502/ijpa.v20i2.19029.
BACKGROUND
The present study was carried out to investigate the prevalence of intestinal microsporidia in patients with intellectual disabilities in the rehabilitation centers of Hormozgan Province in south of Iran, using microscopic and molecular methods.
METHODS
The current cross-sectional study was conducted on 119 stool samples obtained from patients with intellectual disabilities. Acid-fast trichrome staining was used to detect parasites. Moreover, all of the stool samples were assessed for the presence of microsporidia DNA by the PCR method.
RESULTS
The mean age of the subjects was 29 (±12.3) years. All stool samples were examined for microsporidia infection, and only one case of was detected in one of the samples. The results of the nested-PCR test on 119 stool samples showed one case of infection with , corresponding to a prevalence of 0.84%. The nested-PCR test for detected no infections in any of the stool samples.
CONCLUSION
The overall prevalence of microsporidia among patients with intellectual disabilities in Hormozgan rehabilitation centers is low and limited to .
背景
本研究旨在采用显微镜和分子方法，调查伊朗南部霍尔木兹甘省康复中心智障患者肠道微孢子虫的感染率。
方法
对119份来自智障患者的粪便样本进行了当前的横断面研究。采用抗酸三色染色法检测寄生虫。此外，通过聚合酶链反应（PCR）方法评估所有粪便样本中微孢子虫DNA的存在情况。
结果
受试者的平均年龄为29（±12.3）岁。对所有粪便样本进行微孢子虫感染检测，仅在其中一个样本中检测到1例感染。对119份粪便样本进行巢式PCR检测，结果显示1例感染，感染率为0.84%。对其他微孢子虫的巢式PCR检测未在任何粪便样本中检测到感染。
结论
霍尔木兹甘康复中心智障患者中微孢子虫的总体感染率较低，且仅限于某一种微孢子虫。
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