Kazemi Mohsen
Department of Animal Science, Faculty of Agriculture and Animal Science, University of Torbat-e Jam, Torbat-e Jam, Iran.
Vet Med Sci. 2025 Sep;11(5):e70528. doi: 10.1002/vms3.70528.
This article presents a comprehensive evaluation of nanoparticle (NP) applications (1-100 nm) in veterinary medicine and animal science based on a rigorous assessment of studies published primarily in 2024. Key findings highlight three transformative impacts: (1) enhanced nutrition via improved mineral (zinc/selenium/iron NPs) and vitamin bioavailability, (2) advanced targeted drug delivery using liposomal/polymeric nanocarriers and (3) innovative disease control through nano-vaccines and mycotoxin adsorbents. The evidence reveals significant improvements across species (e.g., ruminants, chickens, aquaculture and other farm animals), with documented increases in growth rates, enhanced immune responses and reduced antibiotic usage. However, critical challenges emerge regarding species-specific dosage variations, long-term toxicity concerns and lack of regulatory frameworks. Collectively, the evidence underscores nanotechnology's potential to revolutionize veterinary practice while emphasizing the need for robust safety protocols and tailored species guidelines.
本文基于对2024年主要发表的研究的严格评估,对纳米颗粒(NP,1-100纳米)在兽医学和动物科学中的应用进行了全面评估。主要发现突出了三个变革性影响:(1)通过改善矿物质(锌/硒/铁纳米颗粒)和维生素的生物利用度来增强营养,(2)使用脂质体/聚合物纳米载体实现先进的靶向给药,以及(3)通过纳米疫苗和霉菌毒素吸附剂进行创新疾病控制。证据显示,在各个物种(如反刍动物、鸡、水产养殖动物和其他农场动物)中都有显著改善,记录显示生长速度加快、免疫反应增强且抗生素使用减少。然而,在物种特异性剂量变化、长期毒性问题以及缺乏监管框架方面出现了关键挑战。总体而言,证据强调了纳米技术在革新兽医实践方面的潜力,同时强调了制定强有力的安全协议和量身定制的物种指南的必要性。