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色素减退性蕈样肉芽肿的一个例证病例。

An illustrative case of hypopigmented mycosis fungoides.

作者信息

Michael Karen, Langley Annie R

机构信息

University of Western Ontario Medical School, Windsor, ON, Canada.

Division of Dermatology, Department of Medicine, University of Ottawa, ON, Canada.

出版信息

SAGE Open Med Case Rep. 2025 Jul 31;13:2050313X251359024. doi: 10.1177/2050313X251359024. eCollection 2025.

DOI:10.1177/2050313X251359024
PMID:40756744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12317257/
Abstract

Hypopigmented mycosis fungoides (MF) is a rare variant of mycosis fungoides that creates diagnostic challenges as it can mimic other more common hypopigmented skin conditions clinically. Herein we present a case of a 31-year-old female with hypopigmented MF with typical histopathological features and excellent response to narrow-band ultraviolet B phototherapy combined with mid-potency topical corticosteroids.

摘要

色素减退性蕈样肉芽肿(MF)是蕈样肉芽肿的一种罕见变体,由于其在临床上可模仿其他更常见的色素减退性皮肤病,因此带来了诊断挑战。在此,我们报告一例31岁女性色素减退性MF病例,其具有典型的组织病理学特征,对窄谱中波紫外线光疗联合中效外用糖皮质激素治疗反应良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7794/12317257/1b5e50f416a5/10.1177_2050313X251359024-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7794/12317257/cdf21c2678a1/10.1177_2050313X251359024-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7794/12317257/1b5e50f416a5/10.1177_2050313X251359024-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7794/12317257/cdf21c2678a1/10.1177_2050313X251359024-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7794/12317257/1b5e50f416a5/10.1177_2050313X251359024-fig2.jpg

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本文引用的文献

1
EORTC consensus recommendations for the treatment of mycosis fungoides/Sézary syndrome - Update 2023.EORTC 共识推荐的蕈样肉芽肿/赛泽里综合征治疗方案 - 2023 年更新版。
Eur J Cancer. 2023 Dec;195:113343. doi: 10.1016/j.ejca.2023.113343. Epub 2023 Sep 18.
2
Hypopigmented Mycosis Fungoides: Clinical, Histological, and Immunohistochemical Remission Induced by Narrow-band Ultraviolet B.色素减退性蕈样肉芽肿:窄谱紫外线B诱导的临床、组织学及免疫组化缓解
Indian J Dermatol. 2017 Mar-Apr;62(2):203-206. doi: 10.4103/ijd.IJD_365_16.
3
Mycosis fungoides: case report and literature review.
蕈样肉芽肿:病例报告及文献综述
Clin Med Insights Case Rep. 2014 Sep 3;7:95-8. doi: 10.4137/CCRep.S15724. eCollection 2014.
4
Hypopigmented mycosis fungoides: a review of its clinical features and pathophysiology.色素减退性蕈样肉芽肿:临床特征与病理生理学综述
An Bras Dermatol. 2013 Nov-Dec;88(6):954-60. doi: 10.1590/abd1806-4841.20132336.
5
Efficacy of narrowband ultraviolet B twice weekly for hypopigmented mycosis fungoides in Asians.窄谱中波紫外线每周两次治疗亚洲人色素减退性蕈样肉芽肿的疗效。
Clin Exp Dermatol. 2012 Mar;37(2):149-52. doi: 10.1111/j.1365-2230.2011.04197.x. Epub 2012 Jan 25.