Kodete Chandra Shikhi, Thuraka Bharadwaj, Pasupuleti Vikram, Malisetty Saiteja
School of Technology, Eastern Illinois University, Charleston, IL 61920, USA.
School of Computer Science and Information Systems, Northwest Missouri State University, Maryville, MO 64468, USA.
Muscles. 2024 Aug 21;3(3):271-286. doi: 10.3390/muscles3030024.
Skeletal muscle function is vital for locomotion, posture, and metabolism, significantly impacting overall health and preventing falls, morbidity, and mortality, especially in elderly populations. This systematic review investigates the influence of hormonal fluctuations on skeletal muscle function across different life stages in women, including adolescence, the reproductive years, and menopause. A comprehensive literature search was conducted using databases such as PubMed, Scopus, and Web of Science to identify relevant studies. This review includes 45 studies that met the inclusion criteria, examining the roles of estrogen, progesterone, and other hormones in muscle metabolism, strength, and recovery. The findings highlight significant stage-specific hormonal impacts on muscle function, revealing how puberty, menstrual cycles, pregnancy, and menopause uniquely affect muscle health. Effective hormonal and non-hormonal interventions tailored to each life stage were identified, offering insights for optimizing muscle function and health management in women. This synthesis aims to bridge the gaps in understanding the hormonal regulation of muscle function, providing a foundation for future research and guiding clinical practices.
骨骼肌功能对于运动、姿势和新陈代谢至关重要，对整体健康有重大影响，并能预防跌倒、发病和死亡，在老年人群中尤为如此。本系统综述调查了激素波动对女性不同生命阶段骨骼肌功能的影响，包括青春期、生育期和更年期。通过使用PubMed、Scopus和Web of Science等数据库进行全面的文献检索，以识别相关研究。本综述纳入了45项符合纳入标准的研究，探讨了雌激素、孕激素和其他激素在肌肉代谢、力量和恢复中的作用。研究结果突出了特定阶段激素对肌肉功能的显著影响，揭示了青春期、月经周期、怀孕和更年期如何独特地影响肌肉健康。确定了针对每个生命阶段的有效激素和非激素干预措施，为优化女性肌肉功能和健康管理提供了见解。本综述旨在弥合对肌肉功能激素调节理解上的差距，为未来研究提供基础并指导临床实践。
