Geriatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Phd Course in Nutritional Sciences, University of Milan, 20122 Milan, Italy.
Nutrients. 2019 Aug 23;11(9):1991. doi: 10.3390/nu11091991.
Sarcopenia is an age-related and accelerated process characterized by a progressive loss of muscle mass and strength/function. It is a multifactorial process associated with several adverse outcomes including falls, frailty, functional decline, hospitalization, and mortality. Hence, sarcopenia represents a major public health problem and has become the focus of intense research. Unfortunately, no pharmacological treatments are yet available to prevent or treat this age-related condition. At present, the only strategies for the management of sarcopenia are mainly based on nutritional and physical exercise interventions. The purpose of this review is, thus, to provide an overview on the role of proteins and other key nutrients, alone or in combination with physical exercise, on muscle parameters.
肌肉减少症是一种与年龄相关的、加速的过程,其特征是肌肉质量和力量/功能逐渐丧失。这是一个多因素的过程,与许多不良后果相关,包括跌倒、虚弱、功能下降、住院和死亡。因此,肌肉减少症是一个主要的公共卫生问题,已成为研究的焦点。不幸的是,目前还没有药物治疗方法可预防或治疗这种与年龄相关的疾病。目前,肌肉减少症的管理策略主要基于营养和体育锻炼干预。因此,本综述的目的是概述蛋白质和其他关键营养素单独或与体育锻炼联合使用对肌肉参数的作用。