Klotz Rosa, Tenckhoff Solveig, Probst Pascal
Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.
Study Center of the German Society of Surgery, Heidelberg University Hospital, Heidelberg, Germany.
Innov Surg Sci. 2024 Jul 16;10(2):61-64. doi: 10.1515/iss-2022-0029. eCollection 2025 Jun.
Evidence-based medicine demands treatment options for patients to be based on the current best available evidence. Systematic reviews (SRs) with meta-analyses allow surgeons to make therapeutical decisions in accordance with the highest level of evidence. Also, high-quality SRs support physicians to challenge the colossal amount of new research data created daily. The systematic review working group of the Study Center of the German Society of Surgery (SDGC) has created specific methodological literature regarding surgical SRs, giving recommendations to assess critical risk of bias and to prevent the creation of SRs that do not provide any new insights to the field. SRs should only be considered if there is new clinically relevant data available that allows the SR to create novel evidence. To address the dilemma of new SRs generated without adding new evidence, living systematic reviews and evidence mapping represent an innovative approach, in which SRs are regularly updated with new research data.
循证医学要求为患者提供的治疗方案应基于当前可得的最佳证据。带有荟萃分析的系统评价（SRs）使外科医生能够依据最高级别的证据做出治疗决策。此外，高质量的SRs有助于医生应对每日产生的海量新研究数据。德国外科学会（SDGC）研究中心的系统评价工作组已针对外科SRs制定了特定的方法学文献，给出了评估关键偏倚风险以及防止创建对该领域无任何新见解的SRs的建议。只有在有新的临床相关数据可用，从而使SR能够产生新证据时，才应考虑进行SRs。为解决在未增加新证据的情况下生成新SRs的困境，实时系统评价和证据图谱是一种创新方法，其中SRs会定期用新研究数据进行更新。
