Ueta Ikuo, Jin Nan, Kuwabara Tetsuo, Saito Yoshihiro
Department of Applied Chemistry, University of Yamanashi, 4-3-11 Takeda, Kofu, 400-8511, Japan.
Department of Applied Chemistry and Life Science, Toyohashi University of Technology, 1-1 Hibarigaoka, Tempaku-cho, Toyohashi, 441-8580, Japan.
Anal Sci. 2025 Aug 8. doi: 10.1007/s44211-025-00833-6.
The evaporation of volatile naphthalene compounds incorporated into solid-state cyclodextrins (CDs) was quantitatively evaluated using a solid-phase extraction (SPE) device and high-performance liquid chromatography (HPLC). Initially, an aqueous CD solution was spiked on a quartz filter and dried. Then, solution of naphthalene compounds in acetone was spiked on the filter, resulting in the formation of guest-CD complexes on the filter. The filter was fixed in a filter holder, and the SPE device was connected to the filter holder. Subsequently, clean air was collected via the filter holder and the SPE device using a gas sampling pump. During air sampling, naphthalene compounds evaporated from the filter and were collected on the SPE device. Subsequently, naphthalene compounds in the SPE device and the filter were eluted with acetone, followed by quantification with HPLC. The results indicated that the inclusion in solid-state β-CD suppressed the evaporation of naphthalene compounds. In addition, the inclusion effect was stronger for the dry than for the wet CDs. The inclusion effect was also found to increase with temperature.
利用固相萃取（SPE）装置和高效液相色谱（HPLC）对掺入固态环糊精（CDs）中的挥发性萘化合物的蒸发进行了定量评估。首先，将CD水溶液加样到石英滤膜上并干燥。然后，将萘化合物的丙酮溶液加样到滤膜上，从而在滤膜上形成客体-CD络合物。将滤膜固定在滤膜支架中，并将SPE装置连接到滤膜支架上。随后，使用气体采样泵通过滤膜支架和SPE装置采集清洁空气。在空气采样过程中，萘化合物从滤膜上蒸发并被收集在SPE装置上。随后，用丙酮洗脱SPE装置和滤膜中的萘化合物，然后用HPLC进行定量。结果表明，固态β-CD中的包合作用抑制了萘化合物的蒸发。此外，干燥CDs的包合作用比潮湿CDs更强。还发现包合作用随温度升高而增强。
