Paolino E, Granieri E, Tola M R, Panarelli M A, Carreras M
J Neurol. 1985;232(6):363-5. doi: 10.1007/BF00313837.
The frequency of diabetes mellitus reported in subjects affected by Bell's palsy varies widely. In this investigation, a case-control study, we encountered a frequency of 24.8%. In addition, arterial hypertension and lipid disturbances were found to affect subjects with Bell's palsy more frequently than controls. These findings appear to suggest a primarily ischaemic pathogenesis for most cases of idiopathic peripheral facial paralysis. Furthermore, the finding of significantly lower taste impairment in diabetics than in non-diabetics with Bell's palsy may support the hypothesis of a vascular rather than a metabolic pathogenesis in these cases also. In fact, the vessels supplying the distal portion of the facial nerve, probably more affected in the diabetic patients in order to preserve taste sensation, have such a particular anatomical configuration that this might favour the onset of a diabetic small vessel disease which, in turn, would represent a factor of easier decompensation.
贝尔面瘫患者中报告的糖尿病发生率差异很大。在这项病例对照研究中，我们发现的发生率为24.8%。此外，发现动脉高血压和脂质紊乱在贝尔面瘫患者中比对照组更常见。这些发现似乎表明，大多数特发性周围性面瘫病例主要是缺血性发病机制。此外，糖尿病患者的味觉障碍明显低于非糖尿病贝尔面瘫患者，这一发现也可能支持这些病例中血管性而非代谢性发病机制的假设。事实上，供应面神经远端部分的血管，可能在糖尿病患者中受影响更大，以保留味觉，其解剖结构特殊，这可能有利于糖尿病小血管疾病的发生，而这反过来又可能是更容易失代偿的一个因素。
