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高血糖情况下一例未确诊的大型脓胸非典型表现的病例研究。

Case Study of an Atypical Presentation of a Large Undiagnosed Empyema in the Setting of Hyperglycemia.

作者信息

Bear Cameron, Dow Jane, Pham Andrew, Hafeez Wasif, Siddique Mohamed S

机构信息

Medical Education, Wayne State University School of Medicine, Detroit, USA.

Family Medicine, Detroit Medical Center Grand River Health Center, Detroit, USA.

出版信息

Cureus. 2025 Jul 9;17(7):e87599. doi: 10.7759/cureus.87599. eCollection 2025 Jul.

DOI:10.7759/cureus.87599
PMID:40786408
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12333564/
Abstract

A 58-year-old man with a history of type 2 diabetes mellitus was hospitalized for hyperglycemia. During a review of systems, the patient reported additional symptoms of mild, right-sided pleuritic chest pain. Further investigation revealed dullness to percussion with decreased breath sounds and slight tachycardia on physical exam. Additional workup revealed a 16 cm pleural effusion on CT, despite no fever, no leukocytosis, and mild clinical presentation. Thoracentesis findings revealed empyema, and laboratory analysis identified . Chest tubes were placed and antibiotics administered during a 15-day hospital stay until the patient requested to leave against medical advice. No concerns of respiratory infection were indicated during the patient's initial admission to the emergency department, nor during the patient's previous hospitalization at a different facility one month prior. The patient remained afebrile (except for one recorded mild fever) with no leukocytosis for the entirety of the admission. This case study serves to increase awareness that even a large empyema can go undiagnosed when clinical presentation deviates from the expected and to inform physicians' response to improve patient health outcomes.

摘要

一名有2型糖尿病病史的58岁男性因高血糖住院。在系统回顾期间,患者报告了右侧轻度胸膜炎性胸痛的其他症状。进一步检查发现体格检查时叩诊呈浊音,呼吸音减弱,并有轻度心动过速。尽管没有发热、白细胞增多和临床表现轻微,但进一步检查发现CT显示有16厘米的胸腔积液。胸腔穿刺结果显示为脓胸,实验室分析确定了……。在15天的住院期间放置了胸管并给予了抗生素治疗,直到患者要求自动出院。在患者最初入住急诊科时,以及在一个月前在另一家医院住院期间,均未发现有呼吸道感染的问题。在整个住院期间,患者一直无发热(除了一次记录的低热)且无白细胞增多。本病例研究旨在提高人们的认识,即当临床表现与预期不符时,即使是大量脓胸也可能未被诊断出来,并为医生提供应对措施,以改善患者的健康结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6cc/12333564/c2aed0136671/cureus-0017-00000087599-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6cc/12333564/bbc452348258/cureus-0017-00000087599-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6cc/12333564/c2aed0136671/cureus-0017-00000087599-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6cc/12333564/bbc452348258/cureus-0017-00000087599-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6cc/12333564/c2aed0136671/cureus-0017-00000087599-i02.jpg

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The alterations of innate immunity and enhanced severity of infections in diabetes mellitus.糖尿病患者固有免疫改变及感染加重。
Immunology. 2024 Mar;171(3):313-323. doi: 10.1111/imm.13706. Epub 2023 Oct 17.
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Empyema: An Atypical Presentation.脓胸:一种非典型表现。
Eur J Case Rep Intern Med. 2020 Apr 24;7(7):001631. doi: 10.12890/2020_001631. eCollection 2020.
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From Normal Flora to Brain Abscesses: A Review of .从正常菌群到脑脓肿:综述…… (原文不完整)
Front Microbiol. 2020 May 7;11:826. doi: 10.3389/fmicb.2020.00826. eCollection 2020.
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Effect of tobacco smoking on the risk of developing community acquired pneumonia: A systematic review and meta-analysis.吸烟对社区获得性肺炎发病风险的影响:系统评价和荟萃分析。
PLoS One. 2019 Jul 18;14(7):e0220204. doi: 10.1371/journal.pone.0220204. eCollection 2019.
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Dtsch Arztebl Int. 2019 May 24;116(21):377-386. doi: 10.3238/arztebl.2019.0377.
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The American Association for Thoracic Surgery consensus guidelines for the management of empyema.美国胸外科协会脓胸管理共识指南
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PLoS One. 2013;8(1):e53169. doi: 10.1371/journal.pone.0053169. Epub 2013 Jan 7.
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