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基于非增强CT的脑内肿瘤性出血机器学习分类的可解释人工智能探索

An Explainable AI Exploration of the Machine Learning Classification of Neoplastic Intracerebral Hemorrhage from Non-Contrast CT.

作者信息

Schulze-Weddige Sophia, Baumgärtner Georg Lukas, Orth Tobias, Tietze Anna, Scheel Michael, Wasilewski David, Wattjes Mike P, Hanning Uta, Kniep Helge, Penzkofer Tobias, Nawabi Jawed

机构信息

Department of Radiology, Campus Virchow, Charité-Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, Freie Universität Berlin, Berlin Institute of Health, 13353 Berlin, Germany.

Department of Neuroradiology, Campus Mitte, Charité-Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, Freie Universität Berlin, Berlin Institute of Health, 10117 Berlin, Germany.

出版信息

Cancers (Basel). 2025 Jul 29;17(15):2502. doi: 10.3390/cancers17152502.

DOI:10.3390/cancers17152502
PMID:40805199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12346390/
Abstract

Intracerebral hemorrhage (ICH) associated with primary and metastatic brain tumors presents a significant challenge in neuro-oncology due to the substantial risk of complications [...].

摘要

与原发性和转移性脑肿瘤相关的脑出血在神经肿瘤学中是一个重大挑战，因为并发症风险很高[...]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b61/12346390/f1f20d75a97b/cancers-17-02502-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b61/12346390/3150dbd178a9/cancers-17-02502-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b61/12346390/4684b5d2261d/cancers-17-02502-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b61/12346390/35c518ce8771/cancers-17-02502-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b61/12346390/b4f4bd1d7af0/cancers-17-02502-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b61/12346390/f1f20d75a97b/cancers-17-02502-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b61/12346390/3150dbd178a9/cancers-17-02502-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b61/12346390/4684b5d2261d/cancers-17-02502-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b61/12346390/35c518ce8771/cancers-17-02502-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b61/12346390/b4f4bd1d7af0/cancers-17-02502-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b61/12346390/f1f20d75a97b/cancers-17-02502-g005.jpg

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本文引用的文献

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Clinical and imaging manifestations of intracerebral hemorrhage in brain tumors and metastatic lesions: a comprehensive overview.脑肿瘤和转移瘤中脑出血的临床与影像学表现：全面概述
J Neurooncol. 2024 Dec;170(3):567-578. doi: 10.1007/s11060-024-04811-2. Epub 2024 Sep 2.
2
Editorial: Delay in cancer diagnosis and factors affecting outcomes.社论：癌症诊断延迟及影响预后的因素
Front Public Health. 2024 Jul 12;12:1442764. doi: 10.3389/fpubh.2024.1442764. eCollection 2024.
3
Explainable AI in medical imaging: An overview for clinical practitioners - Beyond saliency-based XAI approaches.
医学成像中的可解释人工智能：临床从业者概述——超越基于显著性的可解释人工智能方法
Eur J Radiol. 2023 May;162:110786. doi: 10.1016/j.ejrad.2023.110786. Epub 2023 Mar 20.
4
An economic impact of incorrect referrals for MRI and CT scans: A retrospective analysis.MRI和CT扫描不当转诊的经济影响：一项回顾性分析。
Health Sci Rep. 2023 Mar 13;6(3):e1102. doi: 10.1002/hsr2.1102. eCollection 2023 Mar.
5
External validation of the diagnostic value of perihematomal edema characteristics in neoplastic and non-neoplastic intracerebral hemorrhage.对肿瘤性和非肿瘤性脑出血perihematomal 水肿特征的诊断价值进行外部验证。
Eur J Neurol. 2023 Jun;30(6):1686-1695. doi: 10.1111/ene.15760. Epub 2023 Mar 23.
6
The Economic Burden of Malignant Brain Tumors.恶性脑肿瘤的经济负担
Adv Exp Med Biol. 2023;1394:209-221. doi: 10.1007/978-3-031-14732-6_13.
7
Increased healthcare costs by later stage cancer diagnosis.晚期癌症诊断导致医疗保健费用增加。
BMC Health Serv Res. 2022 Sep 13;22(1):1155. doi: 10.1186/s12913-022-08457-6.
8
Prophylactic anticoagulation in patients with glioblastoma or brain metastases and atrial fibrillation: an increased risk for intracranial hemorrhage?预防性抗凝治疗胶质母细胞瘤或脑转移瘤合并心房颤动患者：颅内出血风险增加？
J Neurooncol. 2021 May;152(3):483-490. doi: 10.1007/s11060-021-03716-8. Epub 2021 Mar 5.
9
Neoplastic and Non-neoplastic Acute Intracerebral Hemorrhage in CT Brain Scans: Machine Learning-Based Prediction Using Radiomic Image Features.CT脑部扫描中的肿瘤性和非肿瘤性急性脑出血：基于放射组学图像特征的机器学习预测
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