[Cooperative study on the multifactor prevention of ischemic heart disease and its development into an integral program for the prevention of noninfectious diseases].

The authors presented a preliminary analysis of the 5-year implementation of a cooperative trial of multifactor prophylaxis of CHD in Moscow and Kaunas. A stable decrease in the prevalence of arterial hypertension (AH) by 20-25% and smoking by 22%, a decrease in SAP and DAP mean levels and the number of smoked cigarettes as compared to initial levels were noted in the group of active prophylaxis (the 1st group). It caused the reduction of CHD death risk by 13.6%. In the group of comparison with common treatment (the 2nd group) the prevalence of smoking decreased by 11% and arterial hypertension tended towards a rise. The comparison of mortality rates in the 1st and 2nd groups showed that in the 1st group total mortality rates were lower by 21% and CVD mortality rates were lower by 41% as compared to the 2nd group. The most noticeable decrease in 5-year mortality rates was observed among the persons initially attributed to the CHD group. Analysis of mortality with relation to the presence and intensity of smoking habits in Moscow and Kaunas indicated to the association of smoking not only with CHD mortality but also with cancer and total mortality making appropriate the development of an integral approach to the prophylaxis of the main chronic noncommunicable diseases.