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美国和加拿大医生关于用于增加乳汁分泌的药物、草药和营养物质的临床实践调查。

A Survey of U.S. and Canadian Physicians' Clinical Practices Related to Pharmacologic, Herbal, and Nutritional Substances Used to Increase Milk Production.

作者信息

Sadovnikova Anna, Sommers Jan, Oberhelman-Eaton Sara

机构信息

School of Medicine, University of California, Davis, Sacramento, California.

Department of Emergency Medicine, Dalhousie University, Halifax, Nova Scotia Canada.

出版信息

Clin Lact (Amarillo). 2024 Feb;15(1):38-48. doi: 10.1891/cl-2023-0017.

Abstract

INTRODUCTION

Physicians may be asked to prescribe, recommend, or discuss foods, herbs, and medications for low milk supply. It is unclear how factors such as education, experience, and regulations influence clinical practice. The objective was to document physicians' clinical practice surrounding pharmacologic, nutritional, and herbal products for the management of low milk supply.

METHODS

Physicians from two Facebook groups completed an anonymous, online survey about their clinical use of pharmaceutical, supplemental, and nutritional substances perceived to increase milk production. The association between practice patterns and lactation medicine expertise or country for different perceived galactagogues was determined.

RESULTS

A total of 307 physicians completed the primary portion of the survey. There was no difference in the proportion of physicians in Canada or the United States (US) who were defined as lactation medicine experts. Canadian physicians were more likely to prescribe metformin, levothyroxine, and domperidone for low milk supply compared to US-based physicians. Canadians and experts were more likely than US-based and non-expert physicians, respectively, to include herbs in their practice. Patient request, personal and clinical experience, and lack of education, research, or access were frequently selected as reasons for or against using a specific substance.

CONCLUSION

The US FDA ban on domperidone affects low milk supply management in North America. Though Canadian physicians prescribed domperidone without limitations, US physicians were less likely to incorporate it into clinical practice. Despite a lack of evidence, physicians in North America frequently used herbs and foods to increase milk production.

摘要

引言

医生可能会被要求为乳汁分泌不足开具处方、提供建议或讨论相关的食物、草药及药物。目前尚不清楚教育程度、经验和法规等因素如何影响临床实践。本研究的目的是记录医生在使用药物、营养和草药产品管理乳汁分泌不足方面的临床实践。

方法

来自两个脸书群组的医生完成了一项关于他们对被认为可增加乳汁分泌的药物、补充剂和营养物质临床使用情况的匿名在线调查。确定了不同催乳剂的实践模式与泌乳医学专业知识或所在国家之间的关联。

结果

共有307名医生完成了调查的主要部分。在加拿大或美国被定义为泌乳医学专家的医生比例没有差异。与美国医生相比,加拿大医生更有可能为乳汁分泌不足开具二甲双胍、左甲状腺素和多潘立酮。加拿大人和专家分别比美国医生和非专家医生更有可能在实践中使用草药。患者需求、个人和临床经验以及缺乏教育、研究或获取途径经常被选为支持或反对使用特定物质的理由。

结论

美国食品药品监督管理局(FDA)对多潘立酮的禁令影响了北美地区乳汁分泌不足的管理。尽管加拿大医生无限制地开具多潘立酮,但美国医生将其纳入临床实践的可能性较小。尽管缺乏证据,北美地区的医生仍经常使用草药和食物来增加乳汁分泌。

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